Sapio Sciences, LLC

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Sapio Sciences, LLC
Type Limited Liability Company
Industry Laboratory informatics
Headquarters Inner Harbor Center
400 E. Pratt Street
Suite 800
Baltimore, Maryland
, U.S.
Area served U.S.
Products
Website SapioSciences.com
LinkedIn https://www.linkedin.com/company/1341751

Sapio Sciences, LLC develops and distributes laboratory informatics software solutions.


History

Sapio Sciences was originally founded in 2004 to develop software tools to address the growing genotyping need for tools to assist in analyzing genetics data, particularly in relation to Genome Wide Association Studies. Sapio's first product was Exemplar Analytics, which ultimately incorporated over 50 different algorithms and was utilized in numerous published papers in prestigious journals.[1][2][3][4][5] Sapio's was subsequently approached by several customers to develop a LIMS solution that would provide a greater level of flexibility and configurability than traditional LIMS solutions on the market. This led to the development of Exemplar LIMS and its introduction in early 2007.[6]

Sapio quietly discontinued its Examplar Biomarker Discovery product sometime after November 2014.[7]

Technology and products

Exemplar is a versatile software tool that encompasses laboratory information management, electronic laboratory notebook, molecular diagnostics, biomarker discovery, and data management in a single framework.[8] Since its original introduction in 2007, Exemplar has evolved into more than a LIMS solution. Sapio introduced its Workflow Engine in 2008[9], with the goal of being able to address the electronic laboratory notebook market and eliminate paper based recording of lab process information.

Exemplar subsequently added a fully configurable data model which meant that Exemplar could now track virtually any data assuming reasonable constraints on volume.[10] This has led to Exemplar being used as a scientific data management system (SDMS) where it is used to manage large volumes of targeted assay data. Statistics have also be implemented to perform detailed analysis of scientific data within the same environment.

In November 2015, Sapio announced its NGS LIMS was available hosted in the cloud under the software as a service distribution model.[11]

Product architecture

Exemplar is an n-tier product that offers both Java and web-based clients. Multiple databases are supported for data storage including MySQL and Oracle.

Target markets

The general framework and adaptable nature of Exemplar has made it applicable to a broad spectrum of accounts, ranging from large pharmaceuticals to university R&D departments. Exemplar is also being used in highly regulated environments such as part 11, GLP, and CLIA laboratories.[12] The Exemplar family of products are focused on supporting non-profit research labs, commercial entities engaging in the discovery of biomarkers, and commercial companies applying ready-for-market molecular based diagnostics.[13]

Features

Product: Exemplar Dx LIMS
Sample, inventory, and data management
Sample login and management?Y[14]
Sample tracking?Y[14]
Sample and/or result batching?
Task and event scheduling?
Option for manual result entry?
Multiple data viewing methods?
Data and trend analysis?
Data and equipment sharing?
Customizable fields and/or interface?
Query capability?
Import data?
Internal file or data linking?
External file or data linking?
ELN support or integration?Y[14]
Export data to MS Excel?
Raw data management?
Data warehouse?
Deadline control?
Production control?
Project and/or task management?
Inventory management?
Document creation and/or management?
Case management?
Workflow management?Y[14]
Specification management?
Customer and supplier management?Y[14]
Billing management?Y[14]
Quality, security, and compliance
Regulatory compliance?Y[14]
QA / QC functions?
Performance evaluation?
Audit trail?
Chain of custody?
Configurable roles and security?
Data normalization?
Data validation?
Data encryption?
Version control?
Automatic data backup?
Environmental monitoring?
Reporting, barcoding, and printing
Custom reporting?Y[14]
Report printing?
Label support?
Barcode support?
Export to PDF?
Export to MS Word?
Export to HTML and/or XML?
Fax integration?
Email integration?
Base functionality
Administrator management?Y[14]
Modular?
Instrument interfacing and management?Y[14]
Mobile device integration?
Alarms and/or alerts?
Work-related time tracking?
Voice recognition system?
External monitoring?
Messaging?
Multilingual?
Network-capable?
Web client or portal?
Online or integrated help?
Software as a service delivery model?
Usage-based cost?
Industries served
life sciences
Product: Exemplar ELN
Experiment, collaboration,
and data management
Chemical and/or mathematical drawing and calculation?
Chemical and/or spectrum file support?
Task and event scheduling?
Option for manual result entry?Y[15]
Multiple data viewing methods?Y[15]
Data and trend analysis?Y[15]
Data and equipment sharing?Y[15]
Customizable fields and/or interface?Y[15]
Configurable templates and forms?Y[15]
Query capability?Y[15]
Import data?Y[15]
Internal file or data linking?
External file or data linking?
Export data to MS Excel?
Raw data management?
Data warehouse?
Project and/or task management?
Inventory management?Y[15]
Document creation and/or management?
Lab and/or group management?
Experiment management?
Workflow management?
Customer and supplier management?
Quality, security, and compliance
Regulatory compliance?
QA / QC functions?
Performance evaluation?
Audit trail?
Chain of custody?
Configurable roles and security?Y[15]
Data normalization?
Data validation?
Data encryption?
Electronic signatures?Y[15]
Version control?
Automatic data backup?
Reporting, barcoding, and printing
Custom reporting?
Report printing?
Label support?
Barcode support?
Export to PDF?
Export to MS Word?
Export to HTML and/or XML?
Email integration?
Base functionality
Administrator management?Y[15]
Modular?
Instrument interfacing and management?Y[15]
Mobile device integration?Y[15]
Third-party software integration?Y[15]
Alarms and/or alerts?Y[15]
External monitoring?
Messaging?
Bookmarking?
Commenting?
Multilingual?
Network-capable?
Web client or portal?Y[15]
Online or integrated help?
Software as a service delivery model?
Usage-based cost?
Industries served
industry-neutral
Product: Exemplar NGS LIMS
Sample, inventory, and data management
Sample login and management?Y[16]
Sample tracking?Y[16]
Sample and/or result batching?
Task and event scheduling?
Option for manual result entry?
Multiple data viewing methods?Y[16]
Data and trend analysis?
Data and equipment sharing?
Customizable fields and/or interface?
Query capability?
Import data?
Internal file or data linking?
External file or data linking?
ELN support or integration?
Export data to MS Excel?
Raw data management?
Data warehouse?
Deadline control?
Production control?
Project and/or task management?
Inventory management?Y[16]
Document creation and/or management?
Case management?
Workflow management?Y[16]
Specification management?
Customer and supplier management?
Billing management?
Quality, security, and compliance
Regulatory compliance?Y[16]
QA / QC functions?Y[16]
Performance evaluation?
Audit trail?
Chain of custody?
Configurable roles and security?
Data normalization?
Data validation?
Data encryption?
Version control?
Automatic data backup?
Environmental monitoring?
Reporting, barcoding, and printing
Custom reporting?
Report printing?
Label support?
Barcode support?
Export to PDF?
Export to MS Word?
Export to HTML and/or XML?
Fax integration?
Email integration?
Base functionality
Administrator management?Y[16]
Modular?
Instrument interfacing and management?Y[16]
Mobile device integration?
Alarms and/or alerts?
Work-related time tracking?
Voice recognition system?
External monitoring?
Messaging?
Multilingual?
Network-capable?
Web client or portal?Y[16]
Online or integrated help?
Software as a service delivery model?Y[11]
Usage-based cost?
Industries served
life sciences
Product: Exemplar Research LIMS
Sample, inventory, and data management
Sample login and management?Y[17]
Sample tracking?Y[17]
Sample and/or result batching?
Task and event scheduling?
Option for manual result entry?
Multiple data viewing methods?
Data and trend analysis?Y[17]
Data and equipment sharing?
Customizable fields and/or interface?
Query capability?Y[17]
Import data?
Internal file or data linking?
External file or data linking?
ELN support or integration?Y[17]
Export data to MS Excel?
Raw data management?
Data warehouse?
Deadline control?
Production control?
Project and/or task management?
Inventory management?
Document creation and/or management?
Case management?
Workflow management?Y[17]
Specification management?Y[17]
Customer and supplier management?
Billing management?
Quality, security, and compliance
Regulatory compliance?
QA / QC functions?
Performance evaluation?
Audit trail?
Chain of custody?
Configurable roles and security?
Data normalization?
Data validation?
Data encryption?
Version control?
Automatic data backup?
Environmental monitoring?
Reporting, barcoding, and printing
Custom reporting?Y[17]
Report printing?
Label support?
Barcode support?
Export to PDF?
Export to MS Word?
Export to HTML and/or XML?
Fax integration?
Email integration?
Base functionality
Administrator management?Y[17]
Modular?
Instrument interfacing and management?Y[17]
Mobile device integration?
Alarms and/or alerts?
Work-related time tracking?
Voice recognition system?
External monitoring?
Messaging?
Multilingual?
Network-capable?
Web client or portal?
Online or integrated help?
Software as a service delivery model?
Usage-based cost?
Industries served
high-throughput sequencing, life sciences

Pricing

Additional information

References

  1. Shiels, A; Bennett, TM; Knopf, HL; Maraini, G; Li, A; Jiao, X; Hejtmancik, JF (2008). "The EPHA2 gene is associated with cataracts linked to chromosome 1p". Molecular vision 14: 2042–55. PMC 2582197. PMID 19005574. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2582197. 
  2. Davila, Sonia; Hibberd, Martin L.; Hari Dass, Ranjeeta; Wong, Hazel E. E.; Sahiratmadja, Edhyana; Bonnard, Carine; Alisjahbana, Bachti; Szeszko, Jeffrey S. et al (2008). Gojobori, Takashi. ed. "Genetic Association and Expression Studies Indicate a Role of Toll-Like Receptor 8 in Pulmonary Tuberculosis". PLoS Genetics 4 (10): e1000218. doi:10.1371/journal.pgen.1000218. PMC 2568981. PMID 18927625. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2568981. 
  3. Mattapallil, MJ; Sahin, A; Silver, PB; Sun, SH; Chan, CC; Remmers, EF; Hejtmancik, JF; Caspi, RR (2008). "Common genetic determinants of uveitis shared with other autoimmune disorders". Journal of Immunology (Baltimore, Md. : 1950) 180 (10): 6751–9. PMC 2493541. PMID 18453595. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2493541. 
  4. Burgner, David; Davila, Sonia; Breunis, Willemijn B.; Ng, Sarah B.; Li, Yi; Bonnard, Carine; Ling, Ling; Wright, Victoria J. et al (2009). Gibson, Greg. ed. "A Genome-Wide Association Study Identifies Novel and Functionally Related Susceptibility Loci for Kawasaki Disease". PLoS Genetics 5 (1): e1000319. doi:10.1371/journal.pgen.1000319. PMC 2607021. PMID 19132087. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2607021. 
  5. Horvath, Anelia; Boikos, Sosipatros; Giatzakis, Christoforos; Robinson-White, Audrey; Groussin, Lionel; Griffin, Kurt J; Stein, Erica; Levine, Elizabeth et al (2006). "A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia". Nature Genetics 38 (7): 794–800. doi:10.1038/ng1809. PMID 16767104. 
  6. "Sapio Sciences Announces Top 5 Pharma Licenses Exemplar LIMS". LIMSfinder.com. 23 April 2007. http://www.limsfinder.com/BlogDetail.aspx?id=32034_0_3_0_C. Retrieved 29 May 2013. 
  7. "Sapio's Laboratory Information Management (LIMS) Solutions". Sapio Sciences, LLC. 2014. Archived from the original on 04 November 2014. https://web.archive.org/web/20141104122256/http://www.sapiosciences.com/lims_products.php. Retrieved 14 October 2015. 
  8. "About Us". Sapio Sciences, LLC. https://www.sapiosciences.com/about-us. Retrieved 14 October 2015. 
  9. Proffitt, Allison (22 February 2012). "ELN Excellence: The New Lab Notebooks". Bio IT World. Cambridge Healthtech Institute. http://www.bio-itworld.com/2012/02/22/eln-excellence-new-lab-notebooks.html. Retrieved 30 September 2013. 
  10. "Sapio Sciences Exemplar LIMS 4.0". Scientific Computing. 15 June 2010. http://www.scientificcomputing.com/Products-Sapio-Sciences-Exemplar-LIMS-4.0-061510.aspx. Retrieved 29 May 2013. 
  11. 11.0 11.1 "Sapio Announces Exemplar NGS LIMS 2.0 with Hosted Option". Sapio Sciences, LLC. 10 November 2015. https://www.sapiosciences.com/news/Sapio-Announces-Exemplar-NGS-LIMS-2-0-with-Hosted-Option. Retrieved 27 July 2016. 
  12. Russell, John (8 October 2008). "ExonHit Bets on Sapio LIMS". Bio-IT World. http://www.bio-itworld.com/issues/2008/oct/exonhit.html. Retrieved 29 May 2013. 
  13. "Sapio Sciences Exemplar LIMS 4.0 Released" (PDF). Sapio Sciences, LLC. 17 May 2010. http://www.sapiosciences.com/download/LIMS4.0_press_release.pdf‎. Retrieved 30 September 2013. 
  14. 14.0 14.1 14.2 14.3 14.4 14.5 14.6 14.7 14.8 14.9 "Exemplar Dx LIMS". Sapio Sciences, LLC. 2015. https://www.sapiosciences.com/exemplar-dx-lims. Retrieved 14 October 2015. 
  15. 15.00 15.01 15.02 15.03 15.04 15.05 15.06 15.07 15.08 15.09 15.10 15.11 15.12 15.13 15.14 15.15 15.16 "Exemplar ELN". Sapio Sciences, LLC. https://www.sapiosciences.com/exemplar-eln. Retrieved 27 July 2016. 
  16. 16.0 16.1 16.2 16.3 16.4 16.5 16.6 16.7 16.8 16.9 "Exemplar NGS LIMS". Sapio Sciences, LLC. 2015. https://www.sapiosciences.com/exemplar-ngs-lims. Retrieved 14 October 2015. 
  17. 17.0 17.1 17.2 17.3 17.4 17.5 17.6 17.7 17.8 17.9 "Exemplar Research LIMS". Sapio Sciences, LLC. 2015. https://www.sapiosciences.com/exemplar-research-lims. Retrieved 14 October 2015.