https://www.limswiki.org/index.php?action=history&feed=atom&title=File%3AFig1_Pickering_LancetMicrobe2021_2-9.jpg 2026-09-26T13:57:04Z Revision history for this page on the wiki MediaWiki 1.43.9 https://www.limswiki.org/index.php?title=File:Fig1_Pickering_LancetMicrobe2021_2-9.jpg&diff=44218&oldid=prev 2021-09-22T16:48:35Z

<p>Added summary.</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 16:48, 22 September 2021</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">==Summary==</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{Information</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|Description='''Figure 1.''' Comparative sensitivity of six commercial SARS-CoV-2 rapid antigen tests. (''A'') Heatmap comparison of lower limit of detection. (''B'') Association between PFUs/mL and Ct result from qRT-PCR for the SARS-CoV-2 N gene (N Ct value). Error bars represent SD of three independent experiments. (''C'') Association between RNA copy number and N Ct values. Copy number per mL was derived from N qRT-PCR on the Zeptometrix RNA standard (consisting of purified, inactivated viral particles of known RNA copy number per mL). In (B) and (C), points were fitted with a linear regression, with the equation of the line and the R&lt;sup&gt;2&lt;/sup&gt; value shown. Horizontal dashed lines denote Ct values of 25 and 28, as the threshold cutoffs used for sensitivity determinations. (''D'') Tests were evaluated in head-to-head comparisons on a panel of 100 SARS-CoV-2-positive nasopharyngeal swabs. Bars denote the N Ct result for each swab, in ascending order, with the antigen test results for each sample directly below each bar presented as a heatmap. Sensitivity determinations from this sample set are shown on the right. Ct value cutoffs of 25 and 28, corresponding to 1.49 × 106 and 1.65 × 105 RNA copies per mL, or 400 and 50 PFUs/mL, respectively, are indicated, with corresponding sensitivity values for each test at each threshold on the right. PFU = plaque-forming unit; SureScreen-F = SureScreen fluorescent; SureScreen-V = SureScreen visual; N = SARS-CoV-2 nucleocapsid; Ct = cycle threshold; qRT-PCR = real-time RT-PCR.</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|Source={{cite journal |title=Comparative performance of SARS-CoV-2 lateral flow antigen tests and association with detection of infectious virus in clinical specimens: A single-centre laboratory evaluation study |journal=The Lancet Microbe |author=Pickering, S.; Batra, R.; Merrick, B. et al. |volume=2 |issue=9 |pages=e461-e471 |year=2021 |doi=10.1016/S2666-5247(21)00143-9}}</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|Author=Pickering, S.; Batra, R.; Merrick, B. et al.</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|Date=2021</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|Permission=[http://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International]</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">}}</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Licensing ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Licensing ==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{cc-by-4.0}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{cc-by-4.0}}</div></td></tr> <!-- diff cache key limswiki:diff:1.41:old-44217:rev-44218:php=table --> </table>

Shawndouglas https://www.limswiki.org/index.php?title=File:Fig1_Pickering_LancetMicrobe2021_2-9.jpg&diff=44217&oldid=prev 2021-09-22T16:36:54Z

<p></p> <p><b>New page</b></p><div><br /> == Licensing ==<br /> {{cc-by-4.0}}</div>

Shawndouglas