Blank spike

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A blank spike, as defined by the United States Environmental Protection Agency via its SEDD Specification Version 5.2, is "a quality control sample with known amounts of target analytes added to a blank." The EPA adds that "data potentially includes a percent recovery and an expected result for each analyte for which the analyte type is 'spike.' An interference check sample is a type of blank spike where the results for unspiked analytes are of interest."[1]


  1. U.S. Environmental Protection Agency (March 2019). "Appendix A. Data Element Dictionary (DED)" (PDF). SEDD Specification Version 5.2. Retrieved 22 September 2022.