Journal:Mini-review of laboratory operations in biobanking: Building biobanking resources for translational research

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Full article title Mini-review of laboratory operations in biobanking: Building biobanking resources for translational research
Journal Frontiers in Public Health
Author(s) Cicek, Mine S.; Olson, Janet E.
Author affiliation(s) Mayo Clinic
Primary contact cicek dot mine at mayo dot edu
Editors Kilbourne, Amy
Year published 2020
Volume and issue 8
Article # 362
DOI 10.3389/fpubh.2020.00362
ISSN 2296-2565
Distribution license Creative Commons Attribution 4.0 International
Website https://www.frontiersin.org/articles/10.3389/fpubh.2020.00362/full
Download https://www.frontiersin.org/articles/10.3389/fpubh.2020.00362/pdf (PDF)

Abstract

Biobanks have become integral to improving population health. We are in a new era in medicine as patients, health professionals, and researchers increasingly collaborate to gain new knowledge and explore new paradigms for diagnosing and treating disease. Many large-scale biobanking efforts are underway worldwide at the institutional, national, and even international level. When linked with subject data from questionnaires and medical records, biobanks serve as valuable resources in translational research. A biobank must have high-quality biospecimens that meet researcher's needs. Biobank laboratory operations require an enormous amount of support, from lab and storage space, information technology expertise, and a laboratory information management system to logistics for sample movement, quality management systems, and appropriate facilities. A paramount metric of success for a biobank is the concept of every biospecimen coming to the repository belonging to a participant who has something to contribute to research for a healthier future. This article will discuss the importance of biorepository operations, specific to the collection and storage of participants' materials. Specific focus will be given to maintaining the quality of biospecimens, along with the various levels of support biorepositories need to fulfill their purpose and ensure the integrity of each biospecimen is maintained.

Keywords: disaster and risk management, biobanking and biorepositories, laboratory information management system (LIMS), biorepository operations, biospecimen research


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Notes

This presentation is faithful to the original, with only a few minor changes to presentation. A few grammar and spelling errors were also corrected. In some cases important information was missing from the references, and that information was added.