Difference between revisions of "Template:Article of the week"

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(Updated article of the week text.)
(Updated article of the week text.)
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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 OConnor BMCInformatics2010 11-12.jpg|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Stahl BMCResearchNotes2013 6.jpg|240px]]</div>
'''"[[Journal:SeqWare Query Engine: Storing and searching sequence data in the cloud|SeqWare Query Engine: Storing and searching sequence data in the cloud]]"'''
'''"[[Journal:Djeen (Database for Joomla!’s Extensible Engine): A research information management system for flexible multi-technology project administration|Djeen (Database for Joomla!’s Extensible Engine): A research information management system for flexible multi-technology project administration]]"'''


Since the introduction of next-generation DNA sequencers the rapid increase in [[Sequencing|sequencer]] throughput, and associated drop in costs, has resulted in more than a dozen human [[Genomics|genomes]] being resequenced over the last few years. These efforts are merely a prelude for a future in which genome resequencing will be commonplace for both biomedical research and clinical applications. The dramatic increase in sequencer output strains all facets of computational infrastructure, especially databases and query interfaces. The advent of cloud computing, and a variety of powerful tools designed to process petascale datasets, provide a compelling solution to these ever increasing demands.
With the advance of post-genomic technologies, the need for tools to manage large scale data in biology becomes more pressing. This involves annotating and storing data securely, as well as granting permissions flexibly with several technologies (all array types, flow cytometry, proteomics) for collaborative work and data sharing. This task is not easily achieved with most systems available today.


In this work, we present the [[SeqWare]] Query Engine which has been created using modern cloud computing technologies and designed to support databasing information from thousands of genomes. Our backend implementation was built using the highly scalable, NoSQL HBase database from the Hadoop project. We also created a web-based frontend that provides both a programmatic and interactive query interface and integrates with widely used genome browsers and tools. ('''[[Journal:SeqWare Query Engine: Storing and searching sequence data in the cloud|Full article...]]''')<br />
We developed Djeen (Database for Joomla!’s Extensible Engine), a new Research Information Management System (RIMS) for collaborative projects. Djeen is a user-friendly application, designed to streamline data storage and annotation collaboratively. Its database model, kept simple, is compliant with most technologies and allows storing and managing of heterogeneous data with the same system. Advanced permissions are managed through different roles. Templates allow Minimum Information (MI) compliance. ('''[[Journal:Djeen (Database for Joomla!’s Extensible Engine): A research information management system for flexible multi-technology project administration|Full article...]]''')<br />


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''Recently featured'': [[Journal:SaDA: From sampling to data analysis—An extensible open source infrastructure for rapid, robust and automated management and analysis of modern ecological high-throughput microarray data|SaDA: From sampling to data analysis—An extensible open source infrastructure for rapid, robust and automated management and analysis of modern ecological high-throughput microarray data]], [[Journal:Launching genomics into the cloud: Deployment of Mercury, a next generation sequence analysis pipeline|Launching genomics into the cloud: Deployment of Mercury, a next generation sequence analysis pipeline]], [[Journal:Benefits of the community for partners of open source vendors|Benefits of the community for partners of open source vendors]]
''Recently featured'': [[Journal:SeqWare Query Engine: Storing and searching sequence data in the cloud|SeqWare Query Engine: Storing and searching sequence data in the cloud]], [[Journal:SaDA: From sampling to data analysis—An extensible open source infrastructure for rapid, robust and automated management and analysis of modern ecological high-throughput microarray data|SaDA: From sampling to data analysis—An extensible open source infrastructure for rapid, robust and automated management and analysis of modern ecological high-throughput microarray data]], [[Journal:Launching genomics into the cloud: Deployment of Mercury, a next generation sequence analysis pipeline|Launching genomics into the cloud: Deployment of Mercury, a next generation sequence analysis pipeline]]

Revision as of 16:17, 29 February 2016

Fig1 Stahl BMCResearchNotes2013 6.jpg

"Djeen (Database for Joomla!’s Extensible Engine): A research information management system for flexible multi-technology project administration"

With the advance of post-genomic technologies, the need for tools to manage large scale data in biology becomes more pressing. This involves annotating and storing data securely, as well as granting permissions flexibly with several technologies (all array types, flow cytometry, proteomics) for collaborative work and data sharing. This task is not easily achieved with most systems available today.

We developed Djeen (Database for Joomla!’s Extensible Engine), a new Research Information Management System (RIMS) for collaborative projects. Djeen is a user-friendly application, designed to streamline data storage and annotation collaboratively. Its database model, kept simple, is compliant with most technologies and allows storing and managing of heterogeneous data with the same system. Advanced permissions are managed through different roles. Templates allow Minimum Information (MI) compliance. (Full article...)


Recently featured: SeqWare Query Engine: Storing and searching sequence data in the cloud, SaDA: From sampling to data analysis—An extensible open source infrastructure for rapid, robust and automated management and analysis of modern ecological high-throughput microarray data, Launching genomics into the cloud: Deployment of Mercury, a next generation sequence analysis pipeline