Difference between revisions of "Template:Article of the week"

From LIMSWiki
Jump to navigationJump to search
(Updated article of the week text.)
(Updated article of the week text.)
Line 1: Line 1:
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Hernandez BMCSystemsBiology2014 8-Suppl2.jpg|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Mariette BMCGenomics2015 13.jpg|240px]]</div>
'''"[[Journal:STATegra EMS: An experiment management system for complex next-generation omics experiments|STATegra EMS: An experiment management system for complex next-generation omics experiments]]"'''
'''"[[Journal:NG6: Integrated next generation sequencing storage and processing environment|NG6: Integrated next generation sequencing storage and processing environment]]"'''


High-throughput [[sequencing]] assays are now routinely used to study different aspects of genome organization. As decreasing costs and widespread availability of sequencing enable more [[Laboratory|laboratories]] to use sequencing assays in their research projects, the number of samples and replicates in these experiments can quickly grow to several dozens of samples and thus require standardized [[Genome informatics|annotation, storage and management]] of preprocessing steps. As a part of the STATegra project, we have developed an Experiment Management System (EMS) for high throughput omics data that supports different types of sequencing-based assays such as RNA-seq, ChIP-seq, Methyl-seq, etc, as well as proteomics and metabolomics data. The STATegra EMS provides metadata annotation of experimental design, samples and processing pipelines, as well as storage of different types of data files, from raw data to ready-to-use measurements. The system has been developed to provide research laboratories with a freely-available, integrated system that offers a simple and effective way for experiment annotation and tracking of analysis procedures. ('''[[Journal:STATegra EMS: An experiment management system for complex next-generation omics experiments|Full article...]]''')<br />
Next generation [[sequencing]] platforms are now well implanted in sequencing centres and some [[Laboratory|laboratories]]. Upcoming smaller scale machines such as the 454 junior from Roche or the MiSeq from Illumina will increase the number of laboratories hosting a sequencer. In such a context, it is important to provide these teams with an easily manageable environment to store and process the produced reads.
 
We describe a user-friendly information system able to manage large sets of sequencing data. It includes, on one hand, a workflow environment already containing pipelines adapted to different input formats (sff, fasta, fastq and qseq), different sequencers (Roche 454, Illumina HiSeq) and various analyses (quality control, assembly, alignment, diversity studies,…) and, on the other hand, a secured web site giving access to the results. The connected user will be able to download raw and processed data and browse through the analysis result statistics. ('''[[Journal:NG6: Integrated next generation sequencing storage and processing environment|Full article...]]''')<br />
<br />
<br />
''Recently featured'':  
''Recently featured'':  
: ▪ [[Journal:STATegra EMS: An experiment management system for complex next-generation omics experiments|STATegra EMS: An experiment management system for complex next-generation omics experiments]]
: ▪ [[Journal:No specimen left behind: Industrial scale digitization of natural history collections|No specimen left behind: Industrial scale digitization of natural history collections]]
: ▪ [[Journal:No specimen left behind: Industrial scale digitization of natural history collections|No specimen left behind: Industrial scale digitization of natural history collections]]
: ▪ [[Journal:MaPSeq, a service-oriented architecture for genomics research within an academic biomedical research institution|MaPSeq, a service-oriented architecture for genomics research within an academic biomedical research institution]]
: ▪ [[Journal:MaPSeq, a service-oriented architecture for genomics research within an academic biomedical research institution|MaPSeq, a service-oriented architecture for genomics research within an academic biomedical research institution]]
: ▪ [[Journal:Grand challenges in environmental informatics|Grand challenges in environmental informatics]]

Revision as of 14:40, 9 May 2016

Fig1 Mariette BMCGenomics2015 13.jpg

"NG6: Integrated next generation sequencing storage and processing environment"

Next generation sequencing platforms are now well implanted in sequencing centres and some laboratories. Upcoming smaller scale machines such as the 454 junior from Roche or the MiSeq from Illumina will increase the number of laboratories hosting a sequencer. In such a context, it is important to provide these teams with an easily manageable environment to store and process the produced reads.

We describe a user-friendly information system able to manage large sets of sequencing data. It includes, on one hand, a workflow environment already containing pipelines adapted to different input formats (sff, fasta, fastq and qseq), different sequencers (Roche 454, Illumina HiSeq) and various analyses (quality control, assembly, alignment, diversity studies,…) and, on the other hand, a secured web site giving access to the results. The connected user will be able to download raw and processed data and browse through the analysis result statistics. (Full article...)

Recently featured:

STATegra EMS: An experiment management system for complex next-generation omics experiments
No specimen left behind: Industrial scale digitization of natural history collections
MaPSeq, a service-oriented architecture for genomics research within an academic biomedical research institution