Difference between revisions of "Template:Article of the week"

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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig2 Wenig BMCBioinformatics2010 11.jpg|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Vodovnik JofPathInformatics2016 7.jpg|240px]]</div>
'''"[[Journal:OpenChrom: A cross-platform open source software for the mass spectrometric analysis of chromatographic data|OpenChrom: A cross-platform open source software for the mass spectrometric analysis of chromatographic data]]"'''
'''"[[Journal:Diagnostic time in digital pathology: A comparative study on 400 cases|Diagnostic time in digital pathology: A comparative study on 400 cases]]"'''


Today, data evaluation has become a bottleneck in [[Chromatography|chromatographic science]]. Analytical instruments equipped with automated samplers yield large amounts of measurement data, which needs to be verified and analyzed. Since nearly every [[Gas chromatography–mass spectrometry|GC/MS]] instrument vendor offers its own data format and software tools, the consequences are problems with data exchange and a lack of comparability between the analytical results. To challenge this situation a number of either commercial or non-profit software applications have been developed. These applications provide functionalities to import and analyze several data formats but have shortcomings in terms of the transparency of the implemented analytical algorithms and/or are restricted to a specific computer platform. ('''[[Journal:OpenChrom: A cross-platform open source software for the mass spectrometric analysis of chromatographic data|Full article...]]''')<br />
Numerous validation studies in digital pathology confirmed its value as a diagnostic tool. However, a longer time to diagnosis than traditional microscopy has been seen as a significant barrier to the routine use of digital pathology. As a part of our validation study, we compared a digital and microscopic diagnostic time in the routine diagnostic setting.  
 
One senior staff pathologist reported 400 consecutive cases in histology, nongynecological, and fine needle aspiration cytology (20 sessions, 20 cases/session), over 4 weeks. Complex, difficult, and rare cases were excluded from the study to reduce the bias. A primary diagnosis was digital, followed by traditional microscopy, six months later, with only request forms available for both. Microscopic slides were scanned at ×20, digital images accessed through the fully integrated [[laboratory information management system]] (LIMS) and viewed in the image viewer on double 23” displays. ('''[[Journal:Diagnostic time in digital pathology: A comparative study on 400 cases|Full article...]]''')<br />
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Revision as of 17:28, 31 May 2016

Fig1 Vodovnik JofPathInformatics2016 7.jpg

"Diagnostic time in digital pathology: A comparative study on 400 cases"

Numerous validation studies in digital pathology confirmed its value as a diagnostic tool. However, a longer time to diagnosis than traditional microscopy has been seen as a significant barrier to the routine use of digital pathology. As a part of our validation study, we compared a digital and microscopic diagnostic time in the routine diagnostic setting.

One senior staff pathologist reported 400 consecutive cases in histology, nongynecological, and fine needle aspiration cytology (20 sessions, 20 cases/session), over 4 weeks. Complex, difficult, and rare cases were excluded from the study to reduce the bias. A primary diagnosis was digital, followed by traditional microscopy, six months later, with only request forms available for both. Microscopic slides were scanned at ×20, digital images accessed through the fully integrated laboratory information management system (LIMS) and viewed in the image viewer on double 23” displays. (Full article...)

Recently featured:

OpenChrom: A cross-platform open source software for the mass spectrometric analysis of chromatographic data
Custom software development for use in a clinical laboratory
NG6: Integrated next generation sequencing storage and processing environment