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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Cervin JofPathInfo2016 7.jpg|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Naulaerts BioAndBioInsights2016 10.png|240px]]</div>
'''"[[Journal:Improving the creation and reporting of structured findings during digital pathology review|Improving the creation and reporting of structured findings during digital pathology review]]"'''
'''"[[Journal:Practical approaches for mining frequent patterns in molecular datasets|Practical approaches for mining frequent patterns in molecular datasets]]"'''


Today, pathology reporting consists of many separate tasks, carried out by multiple people. Common tasks include dictation during case review, transcription, verification of the transcription, report distribution, and reporting the key findings to follow-up registries. Introduction of digital workstations makes it possible to remove some of these tasks and simplify others. This study describes the work presented at the Nordic Symposium on Digital Pathology 2015, in Linköping, Sweden.
Pattern detection is an inherent task in the analysis and interpretation of complex and continuously accumulating biological data. Numerous [[wikipedia:Sequential pattern mining|itemset mining]] algorithms have been developed in the last decade to efficiently detect specific pattern classes in data. Although many of these have proven their value for addressing bioinformatics problems, several factors still slow down promising algorithms from gaining popularity in the life science community. Many of these issues stem from the low user-friendliness of these tools and the complexity of their output, which is often large, static, and consequently hard to interpret. Here, we apply three software implementations on common [[bioinformatics]] problems and illustrate some of the advantages and disadvantages of each, as well as inherent pitfalls of biological data mining. Frequent itemset mining exists in many different flavors, and users should decide their software choice based on their research question, programming proficiency, and added value of extra features. ('''[[Journal:Practical approaches for mining frequent patterns in molecular datasets|Full article...]]''')<br />
 
We explored the possibility of having a digital tool that simplifies image review by assisting note-taking, and with minimal extra effort, populates a structured report. Thus, our prototype sees reporting as an activity interleaved with image review rather than a separate final step. We created an interface to collect, sort, and display findings for the most common reporting needs, such as tumor size, grading, and scoring. ('''[[Journal:Improving the creation and reporting of structured findings during digital pathology review|Full article...]]''')<br />
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Revision as of 17:59, 25 October 2016

Fig1 Naulaerts BioAndBioInsights2016 10.png

"Practical approaches for mining frequent patterns in molecular datasets"

Pattern detection is an inherent task in the analysis and interpretation of complex and continuously accumulating biological data. Numerous itemset mining algorithms have been developed in the last decade to efficiently detect specific pattern classes in data. Although many of these have proven their value for addressing bioinformatics problems, several factors still slow down promising algorithms from gaining popularity in the life science community. Many of these issues stem from the low user-friendliness of these tools and the complexity of their output, which is often large, static, and consequently hard to interpret. Here, we apply three software implementations on common bioinformatics problems and illustrate some of the advantages and disadvantages of each, as well as inherent pitfalls of biological data mining. Frequent itemset mining exists in many different flavors, and users should decide their software choice based on their research question, programming proficiency, and added value of extra features. (Full article...)

Recently featured:

Improving the creation and reporting of structured findings during digital pathology review
The challenges of data quality and data quality assessment in the big data era
Water, water, everywhere: Defining and assessing data sharing in academia