Difference between revisions of "Template:Article of the week"

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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Closha BMCBioinfo2018 19-Sup1.gif|240px]]</div>
'''"[[Journal:Big data management for cloud-enabled geological information services|Big data management for cloud-enabled geological information services]]"'''
'''"[[Journal:Closha: Bioinformatics workflow system for the analysis of massive sequencing data|Closha: Bioinformatics workflow system for the analysis of massive sequencing data]]"'''


[[Cloud computing]] as a powerful technology of performing massive-scale and complex computing plays an important role in implementing [[Geoinformatics|geological information services]]. In the era of big data, data are being collected at an unprecedented scale. Therefore, to ensure successful data processing and analysis in cloud-enabled geological information services (CEGIS), we must address the challenging and time-demanding task of big data processing. This review starts by elaborating the system architecture and the requirements for big data management. This is followed by the analysis of the application requirements and technical challenges of big data management for CEGIS in China. This review also presents the application development opportunities and technical trends of big data management in CEGIS, including collection and preprocessing, storage and management, analysis and mining, parallel computing-based cloud platforms, and technology applications. ('''[[Journal:Big data management for cloud-enabled geological information services|Full article...]]''')<br />
While next-generation sequencing (NGS) costs have fallen in recent years, the cost and complexity of computation remain substantial obstacles to the use of NGS in bio-medical care and [[Genomics|genomic]] research. The rapidly increasing amounts of data available from the new high-throughput methods have made data processing infeasible without automated pipelines. The integration of data and analytic resources into workflow systems provides a solution to the problem by simplifying the task of data analysis.
 
To address this challenge, we developed a cloud-based workflow management system, Closha, to provide fast and cost-effective analysis of massive genomic data. We implemented complex workflows making optimal use of high-performance computing clusters. Closha allows users to create multi-step analyses using drag-and-drop functionality and to modify the parameters of pipeline tools. ('''[[Journal:Closha: Bioinformatics workflow system for the analysis of massive sequencing data|Full article...]]''')<br />
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Revision as of 15:34, 16 April 2018

Fig1 Closha BMCBioinfo2018 19-Sup1.gif

"Closha: Bioinformatics workflow system for the analysis of massive sequencing data"

While next-generation sequencing (NGS) costs have fallen in recent years, the cost and complexity of computation remain substantial obstacles to the use of NGS in bio-medical care and genomic research. The rapidly increasing amounts of data available from the new high-throughput methods have made data processing infeasible without automated pipelines. The integration of data and analytic resources into workflow systems provides a solution to the problem by simplifying the task of data analysis.

To address this challenge, we developed a cloud-based workflow management system, Closha, to provide fast and cost-effective analysis of massive genomic data. We implemented complex workflows making optimal use of high-performance computing clusters. Closha allows users to create multi-step analyses using drag-and-drop functionality and to modify the parameters of pipeline tools. (Full article...)

Recently featured:

Big data management for cloud-enabled geological information services
Evidence-based design and evaluation of a whole genome sequencing clinical report for the reference microbiology laboratory
Moving ERP systems to the cloud: Data security issues