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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Dufresnes PLOSONE2018 12-1.png|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig9 Pathinarupothi BMCMedInfoDecMak2018 18.png|240px]]</div>
'''"[[Journal:Broad-scale genetic diversity of Cannabis for forensic applications|Broad-scale genetic diversity of Cannabis for forensic applications]]"'''
'''"[[Journal:Data to diagnosis in global health: A 3P approach|Data to diagnosis in global health: A 3P approach]]"'''


''Cannabis'' (hemp and marijuana) is an iconic yet controversial crop. On the one hand, it represents a growing market for pharmaceutical and agricultural sectors. On the other hand, plants synthesizing the psychoactive THC produce the most widespread illicit drug in the world. Yet, the difficulty to reliably distinguish between ''Cannabis'' varieties based on morphological or biochemical criteria impedes the development of promising industrial programs and hinders the fight against narcotrafficking. Genetics offers an appropriate alternative to characterize drug vs. non-drug ''Cannabis''. However, forensic applications require rapid and affordable genotyping of informative and reliable molecular markers for which a broad-scale reference database, representing both intra- and inter-variety variation, is available. Here we provide such a resource for ''Cannabis'', by genotyping 13 microsatellite loci (STRs) in 1,324 samples selected specifically for fiber (24 hemp varieties) and drug (15 marijuana varieties) production. We showed that these loci are sufficient to capture most of the genome-wide diversity patterns recently revealed by [[DNA sequencing#High-throughput methods|next-generation sequencing]] (NGS) data. ('''[[Journal:Broad-scale genetic diversity of Cannabis for forensic applications|Full article...]]''')<br />
With connected medical devices fast becoming ubiquitous in healthcare monitoring, there is a deluge of data coming from multiple body-attached sensors. Transforming this flood of data into effective and efficient diagnosis is a major challenge. To address this challenge, we present a "3P" approach: personalized patient monitoring, precision diagnostics, and preventive criticality alerts. In a collaborative work with doctors, we present the design, development, and testing of a healthcare data analytics and communication framework that we call RASPRO (Rapid Active Summarization for effective PROgnosis). The heart of RASPRO is "physician assist filters" (PAF) that 1. transform unwieldy multi-sensor time series data into summarized patient/disease-specific trends in steps of progressive precision as demanded by the doctor for a patient’s personalized condition, and 2. help in identifying and subsequently predictively alerting the onset of critical conditions. ('''[[Journal:Data to diagnosis in global health: A 3P approach|Full article...]]''')<br />
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Revision as of 15:25, 18 March 2019

Fig9 Pathinarupothi BMCMedInfoDecMak2018 18.png

"Data to diagnosis in global health: A 3P approach"

With connected medical devices fast becoming ubiquitous in healthcare monitoring, there is a deluge of data coming from multiple body-attached sensors. Transforming this flood of data into effective and efficient diagnosis is a major challenge. To address this challenge, we present a "3P" approach: personalized patient monitoring, precision diagnostics, and preventive criticality alerts. In a collaborative work with doctors, we present the design, development, and testing of a healthcare data analytics and communication framework that we call RASPRO (Rapid Active Summarization for effective PROgnosis). The heart of RASPRO is "physician assist filters" (PAF) that 1. transform unwieldy multi-sensor time series data into summarized patient/disease-specific trends in steps of progressive precision as demanded by the doctor for a patient’s personalized condition, and 2. help in identifying and subsequently predictively alerting the onset of critical conditions. (Full article...)

Recently featured:

Building a newborn screening information management system from theory to practice
Adapting data management education to support clinical research projects in an academic medical center
Development of an electronic information system for the management of laboratory data of tuberculosis and atypical mycobacteria at the Pasteur Institute in Côte d’Ivoire