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'''"[[Journal:Defending our public biological databases as a global critical infrastructure|Defending our public biological databases as a global critical infrastructure]]"'''
'''"[[Journal:The development of data science: Implications for education, employment, research, and the data revolution for sustainable development|The development of data science: Implications for education, employment, research, and the data revolution for sustainable development]]"'''


In data science, we are concerned with the integration of relevant sciences in observed and empirical contexts. This results in the unification of analytical methodologies, and of observed and empirical data contexts. Given the dynamic nature of convergence, the origins and many evolutions of the data science theme are described. The following are covered in this article: the rapidly growing post-graduate university course provisioning for data science; a preliminary study of employability requirements; and how past eminent work in the social sciences and other areas, certainly mathematics, can be of immediate and direct relevance and benefit for innovative methodology, and for facing and addressing the ethical aspect of big data [[Data analysis|analytics]], relating to data aggregation and scale effects. ('''[[Journal:The development of data science: Implications for education, employment, research, and the data revolution for sustainable development|Full article...]]''')<br />
Progress in modern biology is being driven, in part, by the large amounts of freely available data in public resources such as the International Nucleotide Sequence Database Collaboration (INSDC), the world's primary database of biological sequence (and related) [[information]]. INSDC and similar databases have dramatically increased the pace of fundamental biological discovery and enabled a host of innovative therapeutic, diagnostic, and forensic applications. However, as high-value, openly shared resources with a high degree of assumed trust, these repositories share compelling similarities to the early days of the internet. Consequently, as public biological databases continue to increase in size and importance, we expect that they will face the same threats as undefended cyberspace. There is a unique opportunity, before a significant breach and loss of trust occurs, to ensure they evolve with quality and security as a design philosophy rather than costly “retrofitted” mitigations. This perspective article surveys some potential quality assurance and security weaknesses in existing open [[Genomics|genomic]] and [[Proteomics|proteomic]] repositories, describes methods to mitigate the likelihood of both intentional and unintentional errors, and offers recommendations for risk mitigation based on lessons learned from [[cybersecurity]]. ('''[[Journal:Defending our public biological databases as a global critical infrastructure|Full article...]]''')<br />
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Revision as of 15:16, 23 July 2019

"Defending our public biological databases as a global critical infrastructure"

Progress in modern biology is being driven, in part, by the large amounts of freely available data in public resources such as the International Nucleotide Sequence Database Collaboration (INSDC), the world's primary database of biological sequence (and related) information. INSDC and similar databases have dramatically increased the pace of fundamental biological discovery and enabled a host of innovative therapeutic, diagnostic, and forensic applications. However, as high-value, openly shared resources with a high degree of assumed trust, these repositories share compelling similarities to the early days of the internet. Consequently, as public biological databases continue to increase in size and importance, we expect that they will face the same threats as undefended cyberspace. There is a unique opportunity, before a significant breach and loss of trust occurs, to ensure they evolve with quality and security as a design philosophy rather than costly “retrofitted” mitigations. This perspective article surveys some potential quality assurance and security weaknesses in existing open genomic and proteomic repositories, describes methods to mitigate the likelihood of both intentional and unintentional errors, and offers recommendations for risk mitigation based on lessons learned from cybersecurity. (Full article...)

Recently featured:

Determining the hospital information system (HIS) success rate: Development of a new instrument and case study
Smart information systems in cybersecurity: An ethical analysis
Chemometric analysis of cannabinoids: Chemotaxonomy and domestication syndrome