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'''"[[Journal:Defending our public biological databases as a global critical infrastructure|Defending our public biological databases as a global critical infrastructure]]"'''
'''"[[Journal:Data science as an innovation challenge: From big data to value proposition|Data science as an innovation challenge: From big data to value proposition]]"'''


Analyzing “big data” holds huge potential for generating business value. The ongoing advancement of tools and technology over recent years has created a new ecosystem full of opportunities for data-driven innovation. However, as the amount of available data rises to new heights, so too does complexity. Organizations are challenged to create the right contexts, by shaping interfaces and processes, and by asking the right questions to guide the [[data analysis]]. Lifting the innovation potential requires teaming and focus to efficiently assign available resources to the most promising initiatives. With reference to the innovation process, this article will concentrate on establishing a process for analytics projects from first ideas to realization (in most cases, a running application). The question we tackle is: what can the practical discourse on big data and analytics learn from innovation management? ('''[[Journal:Data science as an innovation challenge: From big data to value proposition|Full article...]]''')<br />
Progress in modern biology is being driven, in part, by the large amounts of freely available data in public resources such as the International Nucleotide Sequence Database Collaboration (INSDC), the world's primary database of biological sequence (and related) [[information]]. INSDC and similar databases have dramatically increased the pace of fundamental biological discovery and enabled a host of innovative therapeutic, diagnostic, and forensic applications. However, as high-value, openly shared resources with a high degree of assumed trust, these repositories share compelling similarities to the early days of the internet. Consequently, as public biological databases continue to increase in size and importance, we expect that they will face the same threats as undefended cyberspace. There is a unique opportunity, before a significant breach and loss of trust occurs, to ensure they evolve with quality and security as a design philosophy rather than costly “retrofitted” mitigations. This perspective article surveys some potential quality assurance and security weaknesses in existing open [[Genomics|genomic]] and [[Proteomics|proteomic]] repositories, describes methods to mitigate the likelihood of both intentional and unintentional errors, and offers recommendations for risk mitigation based on lessons learned from [[cybersecurity]]. ('''[[Journal:Defending our public biological databases as a global critical infrastructure|Full article...]]''')<br />
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Revision as of 15:16, 23 July 2019

"Defending our public biological databases as a global critical infrastructure"

Progress in modern biology is being driven, in part, by the large amounts of freely available data in public resources such as the International Nucleotide Sequence Database Collaboration (INSDC), the world's primary database of biological sequence (and related) information. INSDC and similar databases have dramatically increased the pace of fundamental biological discovery and enabled a host of innovative therapeutic, diagnostic, and forensic applications. However, as high-value, openly shared resources with a high degree of assumed trust, these repositories share compelling similarities to the early days of the internet. Consequently, as public biological databases continue to increase in size and importance, we expect that they will face the same threats as undefended cyberspace. There is a unique opportunity, before a significant breach and loss of trust occurs, to ensure they evolve with quality and security as a design philosophy rather than costly “retrofitted” mitigations. This perspective article surveys some potential quality assurance and security weaknesses in existing open genomic and proteomic repositories, describes methods to mitigate the likelihood of both intentional and unintentional errors, and offers recommendations for risk mitigation based on lessons learned from cybersecurity. (Full article...)

Recently featured:

Determining the hospital information system (HIS) success rate: Development of a new instrument and case study
Smart information systems in cybersecurity: An ethical analysis
Chemometric analysis of cannabinoids: Chemotaxonomy and domestication syndrome