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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:School Based Health Clinic.jpg|140px]]</div>
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A '''[[federally qualified health center]]''' ('''FQHC''') is a reimbursement designation from the [[Centers for Medicare and Medicaid Services]] (CMS) of the [[United States Department of Health and Human Services]] (HHS). This designation is significant for several health programs funded under Section 330 of the Public Health Service Act, as part of the Health Center Consolidation Act. The FQHC program is designed "to enhance the provision of primary care services in underserved urban and rural communities."
'''"[[Journal:ChromaWizard: An open-source image analysis software for multicolor fluorescence in situ hybridization analysis|ChromaWizard: An open-source image analysis software for multicolor fluorescence in situ hybridization analysis]]"'''


FQHCs are community-based organizations that provide comprehensive primary and preventive care, including health, oral, and mental health services to persons of all ages, regardless of their ability to pay or health insurance status. Thus, they are a critical component of the health care safety net. As of 2011 over 1,100 FQHCs operate approximately 6,000 sites throughout the United States and territories, serving an estimated 20 million patients. That number is expected to go up to 40 million people by 2015 thanks to extra grant funding to the program. FQHCs may also be referred to as community/migrant health centers (C/MHC), community health centers (CHC), and 330 funded clinics. ('''[[Federally qualified health center|Full article...]]''')<br />
Multicolor image analysis finds its applications in a broad range of biological studies. Specifically, multiplex [[wikipedia:Fluorescence in situ hybridization|fluorescence ''in situ'' hybridization]] (M‐FISH) for chromosome painting facilitates the analysis of individual chromosomes in complex metaphase spreads and is widely used to detect both numerical and structural aberrations. While this is well established for human and mouse [[wikipedia:Karyotype|karyotypes]], for which species sophisticated software and analysis tools are available, other organisms and species are less well served. Commercially available software is proprietary and not easily adaptable to other karyotypes. Therefore, a publicly available open-source software that combines flexibility and customizable functionalities is needed. Here we present such a tool, called “ChromaWizard,” which is based on popular scientific image analysis libraries (OpenCV, scikit‐image, and NumPy). We demonstrate its functionality on the example of primary Chinese hamster (''Cricetulus griseus'') fibroblasts metaphase spreads and on Chinese hamster ovary cell lines, known for their large number of chromosomal rearrangements. ('''[[Journal:ChromaWizard: An open-source image analysis software for multicolor fluorescence in situ hybridization analysis|Full article...]]''')<br />
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''Recently featured'': [[Home health agency]], [[ISO 9000]], [[Health Level 7]]
''Recently featured'':
: ▪ [[Journal:Haves and have nots must find a better way: The case for open scientific hardware|Haves and have nots must find a better way: The case for open scientific hardware]]
: ▪ [[Journal:CytoConverter: A web-based tool to convert karyotypes to genomic coordinates|CytoConverter: A web-based tool to convert karyotypes to genomic coordinates]]
: ▪ [[Journal:Implementing a novel quality improvement-based approach to data quality monitoring and enhancement in a multipurpose clinical registry|Implementing a novel quality improvement-based approach to data quality monitoring and enhancement in a multipurpose clinical registry]]

Revision as of 22:58, 24 February 2020

Fig4 Auer CytometryPartA2018 93-7.jpg

"ChromaWizard: An open-source image analysis software for multicolor fluorescence in situ hybridization analysis"

Multicolor image analysis finds its applications in a broad range of biological studies. Specifically, multiplex fluorescence in situ hybridization (M‐FISH) for chromosome painting facilitates the analysis of individual chromosomes in complex metaphase spreads and is widely used to detect both numerical and structural aberrations. While this is well established for human and mouse karyotypes, for which species sophisticated software and analysis tools are available, other organisms and species are less well served. Commercially available software is proprietary and not easily adaptable to other karyotypes. Therefore, a publicly available open-source software that combines flexibility and customizable functionalities is needed. Here we present such a tool, called “ChromaWizard,” which is based on popular scientific image analysis libraries (OpenCV, scikit‐image, and NumPy). We demonstrate its functionality on the example of primary Chinese hamster (Cricetulus griseus) fibroblasts metaphase spreads and on Chinese hamster ovary cell lines, known for their large number of chromosomal rearrangements. (Full article...)

Recently featured:

▪ Haves and have nots must find a better way: The case for open scientific hardware
▪ CytoConverter: A web-based tool to convert karyotypes to genomic coordinates
▪ Implementing a novel quality improvement-based approach to data quality monitoring and enhancement in a multipurpose clinical registry
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