Difference between revisions of "Template:Article of the week"

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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig0 Cardenia JofFoodDrugAnal2018 26-4.jpg|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Anx1 WHO 2020 2020.5.png|240px]]</div>
'''"[[Journal:Development and validation of a fast gas chromatography–mass spectrometry method for the determination of cannabinoids in Cannabis sativa L|Development and validation of a fast gas chromatography–mass spectrometry method for the determination of cannabinoids in Cannabis sativa L]]"'''
'''"[[Journal:Laboratory testing for coronavirus disease (COVID-19) in suspected human cases|Laboratory testing for coronavirus disease (COVID-19) in suspected human cases]]"'''


A routine method for determining [[wikipedia:Cannabinoid|cannabinoids]] in ''Cannabis sativa'' L. [[wikipedia:Inflorescence|inflorescence]], based on fast [[gas chromatography]] coupled to [[mass spectrometry]] (fast GC-MS), was developed and validated. To avoid the [[wikipedia:Decarboxylation|decarboxylation]] of the carboxyl group of cannabinoids, different derivatization approaches—i.e., silylation and esterification (diazomethane-mediated) reagents and solvents (pyridine or ethyl acetate)—were tested. The methylation significantly increased the signal-to-noise ratio of all carboxylic cannabinoids, except for cannabigerolic acid (CBGA). Since [[wikipedia:Diazomethane|diazomethane]] is not commercially available, is considered a hazardous reactive, and requires one-day synthesis by specialized chemical staff, the process of silylation was used along the entire validation of a routine method. The method gave a fast (total analysis time < 7.0 min) and satisfactory resolution (R > 1.1), with a good repeatability (intraday < 8.38%; interday < 11.10%) and sensitivity (LOD < 11.20 ng/mL). ('''[[Journal:Development and validation of a fast gas chromatography–mass spectrometry method for the determination of cannabinoids in Cannabis sativa L|Full article...]]''')<br />
This document provides interim guidance to [[Laboratory|laboratories]] and stakeholders involved in [[COVID-19]] virus laboratory testing of patients. It is based in part on the interim guidance on laboratory testing for [[Middle East respiratory syndrome]] (MERS) coronavirus. [[Information]] on human [[infection]] with the COVID-19 virus is evolving and the [[World Health Organization]] (WHO) continues to monitor developments and revise recommendations as necessary. This document will be revised as new information becomes available. Feedback is welcome and can be sent to WHElab@who.int. The virus has now been named SARS-CoV-2 by the International Committee of Taxonomy of Viruses (ICTV)(2). This virus can cause the disease named coronavirus disease 2019 (COVID-19). WHO refers to the virus as COVID-19 virus in its current documentation. ('''[[Journal:A security review of local government using NIST CSF: A case study|Full article...]]''')<br />
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Revision as of 15:46, 23 March 2020

Anx1 WHO 2020 2020.5.png

"Laboratory testing for coronavirus disease (COVID-19) in suspected human cases"

This document provides interim guidance to laboratories and stakeholders involved in COVID-19 virus laboratory testing of patients. It is based in part on the interim guidance on laboratory testing for Middle East respiratory syndrome (MERS) coronavirus. Information on human infection with the COVID-19 virus is evolving and the World Health Organization (WHO) continues to monitor developments and revise recommendations as necessary. This document will be revised as new information becomes available. Feedback is welcome and can be sent to WHElab@who.int. The virus has now been named SARS-CoV-2 by the International Committee of Taxonomy of Viruses (ICTV)(2). This virus can cause the disease named coronavirus disease 2019 (COVID-19). WHO refers to the virus as COVID-19 virus in its current documentation. (Full article...)

Recently featured:

One tool to find them all: A case of data integration and querying in a distributed LIMS platform
What is the "source" of open-source hardware?
From command-line bioinformatics to bioGUI