Difference between revisions of "User:Shawndouglas/sandbox/sublevel9"

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==Sandbox begins below==
==Sandbox begins below==


As of March 25, 2019
==2. Sample Management==
{|
| STYLE="vertical-align:top;"|
{| class="wikitable collapsible" border="1" cellpadding="10" cellspacing="0"
|-
  ! colspan="2" style="text-align:left; padding-left:20px; padding-top:10px; padding-bottom:10px;"|
|-
  ! style="color:brown; background-color:#ffffee; width:500px;"| Regulation, Specification, or Guidance
  ! style="color:brown; background-color:#ffffee; width:700px;"| Requirement
|-
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-2-1]<br />[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 4.11.14]
  | style="background-color:white;" |'''2.1''' The system shall record and maintain the chain of custody for the laboratory's standards and reagents.
|-
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-2-2]<br />[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 4.11.14]
  | style="background-color:white;" |'''2.2''' The system shall record the current and historical storage location for the laboratory's standards and reagents.
|-
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-2-3]<br />[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 4.11.14]
  | style="background-color:white;" |'''2.3''' The system shall allow the laboratory's previously standardized standards and reagents to be assigned a new standard value.
|-
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-2-4]<br />[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 4.11.14]
  | style="background-color:white;" |'''2.4''' The system shall require the recording of a standard and reagent's first opening date.
|-
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-2-5]<br />[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 4.11.14]
  | style="background-color:white;" |'''2.5''' The system shall allow only active standards and reagents to be shown as available for use.
|-
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-2-6]<br />[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 4.11.14]
  | style="background-color:white;" |'''2.6''' The system shall allow standards and reagents to be flagged as no longer available for use by authorized personnel.
|-
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-2-7]
  | style="background-color:white;" |'''2.7''' The system shall allow logically associated samples to be grouped together based on associated metadata such as sample type, test method, assigned user, and status.
|-
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-2-8]<br />[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 3.2]<br />[https://www.iso.org/standard/66912.html ISO/IEC 17025:2017 7.4.2]
  | style="background-color:white;" |'''2.8''' The system should allow for the accurate identification of a physical sample in the system via barcode or RFID technology.
|-
  | style="padding:5px; width:500px;" |
[https://www.law.cornell.edu/cfr/text/7/331.17 7 CFR Part 331.17]<br />
[https://www.law.cornell.edu/cfr/text/9/121.17 9 CFR Part 121.17]<br />
[https://www.law.cornell.edu/cfr/text/21/211.84 21 CFR Part 211.84]<br />
[https://www.law.cornell.edu/cfr/text/42/73.17 42 CFR Part 73.17]<br />
[https://www.astm.org/Standards/E1492.htm ASTM E1492-11 4.2.1]<br />
[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-2-9]
  | style="background-color:white;" |'''2.9''' The system should provide a means to manually or automatically track sample inventory amounts and status.
|-
  | style="padding:5px; width:500px;" |[http://des.wa.gov/sites/default/files/public/documents/About/1063/RFP/Add7_Item4ASCLD.pdf ASCLD/LAB Supp. Reqs. for the Accreditation of Forensic Science Testing Laboratories 5.9.1.1]<br />[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-2-10]
  | style="background-color:white;" |'''2.10''' The system shall be able to link test methods and specifications to standards and reagents.
|-
  | style="padding:5px; width:500px;" |
[https://www.law.cornell.edu/cfr/text/21/211.84 21 CFR Part 211.84]<br />
[https://www.law.cornell.edu/cfr/text/21/211.166 21 CFR Part 211.166–7]<br />
[https://www.law.cornell.edu/cfr/text/21/211.194 21 CFR Part 211.194 (e)]<br />
[https://www.law.cornell.edu/cfr/text/21/212.40 21 CFR Part 212.40 (c)]<br />
[https://www.law.cornell.edu/cfr/text/21/212.61 21 CFR Part 212.61]<br />
[https://www.law.cornell.edu/cfr/text/21/212.70 21 CFR Part 212.70 (e)]<br />
[https://www.law.cornell.edu/cfr/text/21/225.58 21 CFR Part 225.58]<br />
[https://www.law.cornell.edu/cfr/text/21/226.58 21 CFR Part 226.58]<br />
[https://www.law.cornell.edu/cfr/text/21/606.65 21 CFR Part 606.65 (c)]<br />
[https://www.law.cornell.edu/cfr/text/21/606.151 21 CFR Part 606.151]<br />
[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-2-11]<br />
[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 3.1.2.1]<br />
[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 4.3.2]<br />
[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 4.11.3.2]<br />
[https://www.epa.gov/quality/guidance-quality-assurance-project-plans-epa-qag-5 EPA QA/G-5 2.2.5]<br />
[https://www.ams.usda.gov/datasets/pdp/pdp-standard-operating-procedures USDA Administrative Procedures for the PDP 8.5]<br />
[https://extranet.who.int/prequal/content/who-technical-report-series WHO Technical Report Series, #986, Annex 2, 17.7]<br />
[https://extranet.who.int/prequal/content/who-technical-report-series WHO Technical Report Series, #986, Annex 2, 17.22–25]
  | style="background-color:white;" |'''2.11''' The system shall allow samples and tests to be created and used specifically for capturing data related to unique forms of sampling and testing such as representative sampling, calibration testing, quality control testing, preventative maintenance testing, stability testing, sterility testing, compatibility testing, identity testing, proficiency testing, and service-event-related testing.
|-
|}
|}


'''Alaska''':
==3. Core Laboratory Testing and Experiments==
 
{|
The state boasts 75 Limited and 97 Standard Marijuana Cultivation Facilities. The state differentiates a "limited" facility as one with 500 square feet or less of grow operation space, whereas "standard" facilities have no such limitation.<ref name="SummersCult16">{{cite web |url=http://www.alaskajournal.com/2016-03-21/cultivation-licenses-dominate-marijuana-applications |title=Cultivation licenses dominate marijuana applications |author=Summers, D.J. |work=Alaska Journal of Commerce |date=21 March 2016 |accessdate=25 April 2019}}</ref> To review the entire list of 172 cultivation facilities, go to [https://www.commerce.alaska.gov/web/amco/ https://www.commerce.alaska.gov/web/amco/] and look for the link "Licenses and Applications by Status."
| STYLE="vertical-align:top;"|
 
{| class="wikitable collapsible" border="1" cellpadding="10" cellspacing="0"
Licensing fees for limited are $1,000, and $5,000 for standard.<ref name="AMCOMariLic">{{cite web |url=https://www.commerce.alaska.gov/web/amco/MarijuanaLicenseApplication.aspx |title=Marijuana License Application |author=Alcohol and Marijuana Control Office |publisher=Alaska Department of Commerce, Community, and Economic Development |accessdate=25 April 2019}}</ref>
|-
 
  ! colspan="2" style="text-align:left; padding-left:20px; padding-top:10px; padding-bottom:10px;"|
 
|-
'''Arizona''':
  ! style="color:brown; background-color:#ffffee; width:500px;"| Regulation, Specification, or Guidance
 
  ! style="color:brown; background-color:#ffffee; width:700px;"| Requirement
The government ties cultivation to dispensaries. However, Arizona state law prohibits making public a list of dispensaries, so the state's cultivators/dispensaries are not publicly known.<ref name="AZDHSFAQsDisp">{{cite web |url=https://www.azdhs.gov/licensing/medical-marijuana/index.php#faqs-dispensary |work=FAQs - Dispensary |title=DI31: Can I get a list of the dispensaries? |author=Arizona Department of Health Services |publisher=Government of Arizona |accessdate=25 April 2019}}</ref>
|-
 
  | style="padding:5px; width:500px;" |
 
[https://www.law.cornell.edu/cfr/text/21/211.84 21 CFR Part 211.84 (d)]<br />[http://des.wa.gov/sites/default/files/public/documents/About/1063/RFP/Add7_Item4ASCLD.pdf ASCLD/LAB Supp. Reqs. for the Accreditation of Forensic Science Testing Laboratories 5.1.3.1]<br />[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-3-1]<br />[https://www.iso.org/standard/56115.html ISO 15189:2012 5.3.2.7]
'''Arkansas''':
  | style="background-color:white;" |'''3.1''' The system shall be able to record the identity of any standards and reagents used in laboratory testing, as well as for each sample or test during result entry. Linked to their identity should also be manufacturer and supplier information (such as certificates of testing); lot numbers; reception, preparation, and expiry dates; name of preparer; reliability testing results; and approval for use.
 
|-
The five cultivation facilities for Arkansas are<ref name="FieldBuild19">{{cite web |url=https://www.arkansasonline.com/news/2019/jan/21/building-underway-all-cannabis-cultivation-sites/ |title=Building underway at all medical marijuana cultivation sites in Arkansas |author=Field, H. |work=Arkansas Democrat Gazette |date=21 January 2019 |accessdate=25 April 2019}}</ref>:
  | style="padding:5px; width:500px;" |[https://www.law.cornell.edu/cfr/text/21/211.84 21 CFR Part 211.84 (e)]<br />[https://www.law.cornell.edu/cfr/text/42/493.1252 42 CFR Part 493.1252 (d)]<br />[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-3-2]
 
  | style="background-color:white;" |'''3.2''' The system shall allow users to only select approved, non-expired standards and reagents for tests and experiments.
* Bold Team, LLC (Cotton Plant)
|-  
* Delta Medical Cannabis Co. (Newport)
  | style="padding:5px; width:500px;" |[https://www.law.cornell.edu/cfr/text/42/493.1252 42 CFR Part 493.1252 (d)]<br />[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-3-3]
* Natural State Medicinals Cultivation, LLC (White Hall)
  | style="background-color:white;" |'''3.3''' The system shall prevent standards, reagents, and other media from being used in testing if they would expire during the testing.
* Natural State Wellness Enterprises, LLC (Newport)
|-
* Osage Creek Cultivation, LLC (Berryville)
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-3-4]
 
  | style="background-color:white;" |'''3.4''' The system shall be able to check physical, control, and specification limits for an instrument sample.
As of March 15, 2019, three of the five were up and running: Bold Team, Osage Creek Cultivation, and Natural State Medicinals Cultivation.<ref name="BrantleyThird19">{{cite web |url=https://www.arktimes.com/ArkansasBlog/archives/2019/03/15/third-marijuana-cultivation-facility-now-operating |title=Third marijuana cultivation facility now operating |author=Brantley, M. |work=Arkansas Times |date=15 March 2019 |accessdate=25 April 2019}}</ref>
|-
 
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-3-6]
The five facilities were licensed after paying a $100,000 license fee and a $500,000 performance bond.<ref name="GrabensteinArk18">{{cite web |url=https://www.usnews.com/news/best-states/arkansas/articles/2018-07-10/ark-medical-marijuana-panel-issues-5-cultivation-licenses |title=Arkansas Issues 5 Medical Marijuana Cultivation Licenses |author=Grabenstein, H. |work=U.S. News |date=10 July 2018 |accessdate=25 April 2019}}</ref>
  | style="background-color:white;" |'''3.5''' The system should allow result entry for all tests linked to a single sample, as well as for multiple samples linked to a single test.
 
|-
 
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-3-7]
'''California''':
  | style="background-color:white;" |'''3.6''' The system should allow user-definable result entry methods, e.g., uploading from a spreadsheet.
 
|-
The state of California has more than 550 unique temporary cannabis cultivators, more than 140 unique adult-use cultivators, and more than 160 unique medicinal-use cultivators. As of January 1, 2019, the state no longer has the authority to issue temporary licenses, though normal adult-use and medicinal-use cultivation licenses can still be applied for.<ref name="CalCanNotice19">{{cite web |url=https://cannabis.ca.gov/2019/01/08/notice-regarding-temporary-cannabis-cultivation-license-applications/ |title=Notice Regarding Temporary Cannabis Cultivation License Applications |author=CalCannabis Cultivation Licensing |work=California Cannabis Portal |publisher=Government of California |date=07 January 2019 |accessdate=25 April 2019}}</ref> To review the entire list of more than 850 unique cultivation businesses (note: some companies have more than one license), go to [https://aca6.accela.com/CALCANNABIS/Cap/CapHome.aspx?module=Licenses https://aca6.accela.com/CALCANNABIS/Cap/CapHome.aspx?module=Licenses], select the license type, then select "Active" from the License Status. (Active licenses won't be older than January 1, 2018.)
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-3-8]
 
  | style="background-color:white;" |'''3.7''' The system should allow outsourced samples to be tracked for aliquoting, chain-of-custody, results entry, and approval purposes.
Application and license fees vary depending on facility type. Consult [https://cannabis.ca.gov/faqs/ the FAQ's] "How much do application/license fees cost?" for the latest regulatory text indicating these fees.
|-
 
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-3-9]
 
  | style="background-color:white;" |'''3.8''' The system shall allow the creation and assignment of retest workflow, while allowing the system or assigned user to determine the existence of a retesting due date and whether or not a new sample is required for the retest.
'''Colorado''':
|-
 
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-3-10]
The state has more than 360 unique medical-use and more than 510 unique adult-use cultivators. To review the two lists in their entirety, go to [https://www.colorado.gov/pacific/enforcement/med-licensed-facilities https://www.colorado.gov/pacific/enforcement/med-licensed-facilities] and select the PDF or Excel file labeled "Cultivations" under each column.
  | style="background-color:white;" |'''3.9''' The system shall support, at a minimum, the floating point/real number, integer number, text, date, list, file, calculated, Boolean, and interval test result data types, allowing users to define the data type for specific test results.
 
|-
Cultivation application and license fees vary based upon operation size. The base fee for everyone is Tier 1 (1 – 1,800 plants) - $1,500.00.<ref name="ColRetail17">{{cite web |url=https://www.colorado.gov/pacific/sites/default/files/Complete%20Retail%20Marijuana%20Rules%20as%20of%20April%2014%202017%20with%20DOR%20Disclaimer_1.pdf |format=PDF |title=Retail Marijuana Rules - 1 CCR 212-2 |author=Department of Revenue, Marijuana Enforcement Division |publisher=Government of Colorado |date=14 April 2017 |accessdate=26 April 2019}}</ref>
  | style="padding:5px; width:500px;" |[https://www.aihaaccreditedlabs.org/Policies/Pages/default.aspx AIHA-LAP Policies 2018 2A.7.8.2]<br />[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-3-11]
 
  | style="background-color:white;" |'''3.10''' The system shall allow users to enter operators such as <, >, +, and - with numeric test results.
For cultivators who wish to expand their operations, the following is paid in addition to the Tier 1 fee<ref name="ColRetail17" />:
|-
 
  | style="padding:5px; width:500px;" |[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-3-12]
* Tier 2 (1,801 – 3,600 plants) - $1,000.00
  | style="background-color:white;" |'''3.11''' The system should allow inter- and intra-assay calculations to be performed, including the use of advanced math functions.
* Tier 3 (3,601 – 6,000 plants) - $2,000.00
|-
* Tier 4 (6,001 – 10,200 plants) - $4,000.00
  | style="padding:5px; width:500px;" |[https://www.law.cornell.edu/cfr/text/42/493.1241 42 CFR Part 493.1241]<br />[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-3-13]<br />[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 4.9.11]
* Tier 5 (10,201 – 13,800 plants) - $6,000.00
  | style="background-color:white;" |'''3.12''' The system should effectively alert users upon entry of out-of-specification test results.
* Each additional tier of 3,600 plants over Tier 5 - $1,000.00
|-
 
  | style="padding:5px; width:500px;" |
 
[https://www.law.cornell.edu/cfr/text/21/211.194 21 CFR Part 211.194]<br />
'''Connecticut''':
[https://www.law.cornell.edu/cfr/text/21/212.60 21 CFR Part 212.60 (g)]<br />
 
[https://www.law.cornell.edu/cfr/text/21/606.160 21 CFR Part 606.160]<br />
According to Connecticut's [https://www.elicense.ct.gov/Lookup/LicenseLookup.aspx license lookup] for medical marijuana producers, the four entities are licensed to cultivate in the state:
[https://www.astm.org/Standards/E1578.htm ASTM E1578-18 C-3-14]<br />
 
[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 3.1.2.3–4]<br />
* [https://advancedgrowlabs.com/ Advanced Grow Labs, LLC]
[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 3.2]<br />
* [http://www.ctpharma.com/ Connecticut Pharmaceutical Solutions, LLC]
[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 4.3.4]<br />
* [https://ct.curaleaf.com/ Curaleaf, LLC]
[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 4.8.1–4]<br />
* [http://theraplant.com/ Theraplant, LLC]
[https://www.epa.gov/sites/production/files/documents/erln_lab_requirements.pdf EPA ERLN Laboratory Requirements 4.11.16]<br />
 
[https://www.ams.usda.gov/datasets/pdp/pdp-standard-operating-procedures USDA Data and Instrumentation for PDP 5.4.2]<br />
The state is not currently accepting new applications. However, the application fees for licenses were $25,000 for the initial applications, a $75,000 registration fee, and a $75,000 renewal fee.<ref name="DCPMedical">{{cite web |url=https://portal.ct.gov/DCP/Medical-Marijuana-Program/Medical-Marijuana-Producer-License |title=Medical Marijuana Producer License |author=Department of Consumer Protection |publisher=Government of Connecticut |accessdate=26 April 2019}}</ref>
[https://www.ams.usda.gov/datasets/pdp/pdp-standard-operating-procedures USDA Data and Instrumentation for PDP 8.1.3]<br />
 
[https://extranet.who.int/prequal/content/who-technical-report-series WHO Technical Report Series, #986, Annex 2, 15.8]
 
  | style="background-color:white;" |'''3.13''' The system shall be able to record a complete record of all data created in the course of a test or experiment, including instruments used, calculations performed, and associated graphs, charts, and spectra. The record should also be able to capture the signatures of those who performed the test or experiment, as well as those who reviewed the record for compliance purposes.
'''Delaware''':
|-  
 
|}
The state's cultivation facilities are vertically integrated with its dispensaries, i.e., dispensaries are also cultivators. The three entities operating cultivation centers in Delaware are<ref name="FishmanSecond17">{{cite web |url=https://www.delawareonline.com/story/news/local/2017/08/02/second-new-castle-county-medical-marijuana-dispensary-set-open/534020001/ |title=Second New Castle County medical marijuana dispensary set to open |author=Fishman, M. |work=Delaware Online |date=02 August 2017 |accessdate=26 April 2019}}</ref>:
|}
 
* [https://col-care.com/delaware/ Columbia Care, LLC]
* Compassionate Care Research Institute, Inc. (Newark)
* [https://www.firststatecompassion.com/ First State Compassion Center, Inc.] (two locations)
 
These compassion centers pay a $40,000 license fee ever two years.<ref name="DHSSDela16">{{cite web |url=https://dhss.delaware.gov/dhss/dph/hsp/files/mmpannrpt2015.pdf |format=PDF |title=Delaware Medical Marijuana Program Annual Report 2015 |author=Delaware Health and Social Services |publisher=Government of Delaware |date=January 2016 |accessdate=26 April 2019}}</ref>
 
The state is not currently accepting new applications.
 
 
'''District of Columbia''':
 
The District of Columbia allows eight cultivators to operate<ref name="DCHMed19">{{cite web |url=https://dchealth.dc.gov/sites/default/files/dc/sites/doh/publication/attachments/MMPProgramUpdateMemo%20website%2003.20.2019.pdf |format=PDF |title=Medical Marijuana and Integrative Therapy Update |author=DC Health |publisher=Government of the District of Columbia |date=20 March 2019 |accessdate=26 April 2019}}</ref>:
 
* Abatin Wellness Center Of The District Of Columbia, LLC
* Apelles Investment Management, LLC
* [https://www.districtgrowers.com/our-mission District Growers, LLC]
* Holistic Remedies, LLC
* Montana Apothecary, LLC dba Alternative Solutions
* Organic Wellness, LLC
* Phyto Management, LLC
* VentureForth, LLC dba CenterCity Cultivation
 
The state is not currently accepting new applications.
 
 
'''Florida''':
 
The state's cultivation is vertically integrated with it its other cannabis functions, and "medical marijuana treatment centers are the only businesses allowed to grow, process or sell
medical marijuana in Florida."<ref name="OMMUUpdate19-4">{{cite web |url=https://s27415.pcdn.co/wp-content/uploads/ommu_updates/2019/041919-OMMU-Update.pdf |format=PDF |title=OMMU Update |author=Office of Medical Marijuana Use |publisher=Government of Florida |date=19 April 2019 |accessdate=26 April 2019}}</ref> However, vertical integration may be removed as a requirement in 2019.<ref name="SomersetFlor19">{{cite web |url=https://www.forbes.com/sites/sarabrittanysomerset/2019/01/25/florida-cannabis-market-is-getting-rid-of-vertical-integration/#2fae72a1cd3c |title=Florida Governor Wants To Modify Its Marijuana Market |author=Somerset, S.B. |work=Forbes |date=25 January 2019 |accessdate=26 April 2019}}</ref> The state currently has 14 medical marijuana treatment centers<ref name="OMMUUpdate19-4" />:
 
* [https://3boysfarms.com/ 3 Boys Farm, LLC]  
* Acreage Florida, Inc. dba Green Owl Pharms<ref name="PRNewsAcreage19">{{cite web |url=https://www.prnewswire.com/news-releases/acreage-holdings-acquires-natures-way-nursery-of-miami-inc-300773215.html |title=Acreage Holdings Acquires Nature's Way Nursery of Miami, Inc. |work=PR Newswire |publisher=PR Newswire Association LLC |date=04 January 2019 |accessdate=26 April 2019}}</ref>
* [https://col-care.com/florida/ CCF HoldCo, LLC dba Columbia Care Florida]
* [https://fl.curaleaf.com/ Curaleaf Florida, LLC dba Curaleaf]
* [https://www.libertyhealthsciences.com/ DFMMJ Investments, LLC dba Liberty Health Sciences]
* [https://fl.risecannabis.com/ Green Thumb Industries Investments, LLC dba RiSE Dispensaries]
* [https://www.growhealthy.com/ GrowHealthy Farms Florida, LLC dba GrowHealthy]
* [https://harvestoffl.com/ Harvest Health & Recreation, Inc.]
* [https://knoxmedical.com/ Knox Management Services, LLC dba Knox Medical] (Going through a name change)
* [https://medmen.com/ MM Enterprises, USA, LLC dba MedMen]
* [https://altmedflorida.com/ NuTrae, LLC dba AltMed Florida (MüV)]
* [https://www.surterra.com/ Surterra Holdings, Inc. dba Surterra Wellness]
* [http://trulieve.com/ Trulieve, Inc.]
* [https://www.vidacann.com/ Vidacann, Ltd.]
 
The state is not currently accepting new applications. It's application fee was reported to be $60,830.<ref name="RosicaLegis18">{{cite web |url=https://floridapolitics.com/archives/258425-legislature-medical-marijuana-budget |title=Legislature slashing Health Dep’t pay because of medical marijuana delays |author=Rosica, J. |work=Florida Politics |publisher=Peter Schorsch |date=09 March 2018 |accessdate=26 April 2019}}</ref>
 
 
'''Hawaii''':
 
The state of Hawaii allows for eight entities to grow and distribute medical marijuana, with each entity able to have two production centers and two dispensaries. Each production center is limited to a maximum of 5,000 cannabis plants. Those eight entities are<ref name="DOHHaw18">{{cite web |url=https://health.hawaii.gov/news/files/2018/08/18-070-DOH-approves-production-center-for-Hawaiian-Ethos.pdf |format=PDF |title=Hawai‘i Department of Health approves production center for medical cannabis licensee Hawaiian Ethos, LLC |author=Hawai'i Department of Health |publisher=Government of Hawai'i |date=14 August 2018 |accessdate=26 April 2019}}</ref>:
 
* [https://www.alohagreen.org/ Aloha Green Holdings, Inc. dba Aloha Green Apothecary]
* [https://greenaloha.com/ Green Aloha, Ltd.]
* [https://www.hawaiianethos.com/ Hawaiian Ethos, LLC]
* [https://www.bigislandgrown.co/ Lau Ola, LLC dba Big Island Grown (B.I.G.) Dispensaries]
* [https://www.noacares.com/ Mānoa Botanicals, LLC dba Noa Botanicals]
* [https://www.mauigrown.com/ Maui Wellness Group, LLC dba Maui Grown Therapies]
* [https://ponolifesciences.com/ Pono Life Sciences, LLC]
* [https://cureoahu.com/ TCG Retro Market 1, LLC dba Cure Oahu]
 
The state is not currently accepting new applications. It's application fee was $5,000, initial license fee $75,000, and license renewal fee $50,000.<ref name="HB321">{{cite web |url=https://www.capitol.hawaii.gov/session2015/bills/HB321_CD1_.HTM |title=HB No. 321 - A bill for an act relating to medical marijuana |publisher=Government of Hawaii |date=2015 |accessdate=26 April 2019}}</ref>
 
 
'''Illinois''':
 
Illinois law allows up to 22 cultivation centers to be established in the state, with the intent being to create a center in each police district. The current cultivation centers are (some entities have centers in more than one district)<ref name="IDAMedical">{{cite web |url=https://www2.illinois.gov/sites/agr/Plants/MCPP/Pages/default.aspx |title=Medical Cannabis Pilot Program |author=Illinois Department of Agriculture |publisher=Government of Illinois |accessdate=26 April 2019}}</ref><ref name="CPAIllinois16">{{cite web |url=http://www.cannabispolicyadviser.com/illinois-medical-cannabis-cultivation-centers/ |title=Illinois cultivation center names locations medical cannabis |author=Cannabis Policy Adviser |date=25 August 2016 |accessdate=26 April 2019}}</ref>:
 
* [https://ataraxiamm.com/ Ataraxia, LLC]
* [https://www.bedfordgrow.com/ Bedford Grow, LLC]
* [http://www.compassventuresinc.com/ Compass Ventures, Inc.]
* [https://www.crescolabs.com/ Cresco Labs, LLC]
* [https://col-careil.com/ Curative Health Cultivation, LLC dba Columbia Care Illinois]
* Effingham Medicinal Farms, LLC
* [https://www.gtigrows.com/ GTI Oglesby LLC and GTI Rock Island, LLC]
* [http://www.iesoillinois.com/page/homepage IESO, LLC]
* [https://ilgrownmedicine.com/ Illinois Grown Medicine, LLC]
* [http://www.ingrownfarms.com/ In Grown Farms, LLC]
* [https://naturesgraceandwellness.com/ Nature’s Grace and Wellness, LLC]
* [https://www.pharmacann.com/ PharmaCann, LLC]
* [http://www.ptsillinois.com/ Progressive Treatment Solutions, LLC]
* [https://www.revolutionenterprises.org/ Revolution Cannabis - Barry, LLC and Revolution Cannabis - Delavan, LLC]
* [http://www.sccsil.org/ Shelbyville County Community Services, Inc.]
* [https://wgpharms.com/ Wellness Group Pharms, LLC]
 
The state is not currently accepting new applications. Fees associated with a cultivation center include a $25,000 application fee, a $200,000 first-year license fee, and a $100,000 annual license fee afterwards.<ref name="IDAMedical15">{{cite web |url=https://www2.illinois.gov/sites/mcpp/Documents/mcppfaq-Updated-2-19-15.pdf |format=PDF |title=Medical Cannabis Pilot Program Frequently Asked Questions |author=Illinois Department of Agriculture |publisher=Government of Illinois |date=18 February 2015 |accessdate=26 April 2019}}</ref>
 
 
'''Louisiana''':
 
Difficulties meeting laboratory testing requirements and acquisitions involving a grow operation have slowed down the progress of getting the state's growing operations started.<ref name="KarlinLouisiana18">{{cite web |url=https://www.theadvocate.com/baton_rouge/news/business/article_b05f7ca4-d6fe-11e8-b997-8ff7036b6c47.html |title=Louisiana medical marijuana delayed after state forced to do product testing, company says |author=Karlin, S. |work=The Acadiana Advocate |date=23 October 2018 |accessdate=26 April 2019}}</ref><ref name="APOneOf18">{{cite web |url=https://www.houmatoday.com/news/20181113/1-of-louisianas-medical-marijuana-growers-has-new-operator?rssfeed=true |title=1 of Louisiana’s medical marijuana growers has new operator |author=The Associated Press |work=Houma Today |date=13 November 2018 |accessdate=26 April 2019}}</ref> Two growing operations are coming online in 2019, however.<ref name="KarlinLimited19">{{cite web |url=https://www.theadvocate.com/acadiana/news/business/article_54507c34-4f34-11e9-85af-6b2bbb7d622c.html |title='Limited release' of marijuana slated for May, with full supply in the fall, grower says |author=Karlin, S. |work=The Acadiana Advocate |date=25 March 2019 |accessdate=26 April 2019}}</ref> Those operations are<ref name="KarlinLimited19" /><ref name="APOneOf18" />:
 
* [https://gbsciences.com/louisiana/ GBSciences, Inc.], hired by Louisiana State University
* [https://www.ilerahealthcare.com/ Ilera Holistic Healthcare], which bought Advanced Biomedics, originally hired by Southern University
 
 
'''Maine''':
 
Cultivation and manufacturing is vertically integrated with dispensaries. The state currently allows for eight such facilities, which are run by five entities<ref name="MMMPList">{{cite web |url=https://www.maine.gov/dafs/bbm/mmmp/list-of-dispensaries |title=List of Dispensaries |work=Maine Medical Use of Marijuana Program |author=Department of Administrative and Financial Services |publisher=Government of Maine |accessdate=27 April 2019}}</ref>:
 
* [http://canuvo.org/ Canuvo, Inc.]
* [https://mainewellness.org/ Northeast Patients Group dba Wellness Connection of Maine] (four locations)
* [http://www.maineorganictherapy.org/ Primary Organic Therapy, Inc. dba Maine Organic Therapy]
* [https://me.curaleaf.com/ Remedy Compassion Center, Inc. dba CuraLeaf Auburn]
* [http://safealternativesmaine.org/ Safe Alternatives]
 
Applications don't currently appear to be accepted. Registration fees were $12,000, and a moving fee of $4,000 was also required.<ref name="MMMPArchives">{{cite web |url=https://www.maine.gov/dafs/bbm/mmmp/archives-other |title=Archives / Other |work=Maine Medical Use of Marijuana Program |author=Department of Administrative and Financial Services |publisher=Government of Maine |accessdate=27 April 2019}}</ref>
 
 
'''Maryland''':
 
The state does not require vertical integration among its growers, dispensaries, and producers, but many growers may also be integrated with dispensaries, etc. Maryland currently has 14 licensed growers<ref name="MMCCCannaInd">{{cite web |url=https://mmcc.maryland.gov/Pages/industry.aspx |title=Cannabis Industry Information |author=Maryland Medical Cannabis Commission |publisher=Government of Maryland |accessdate=27 April 2019}}</ref>:
 
* [https://curiowellness.com/ Curio Cultivation, LLC]
* Doctors Orders Maryland, LLC
* [https://forwardgro.com/ ForwardGro, LLC]
* [http://www.freestate-wellness.com/ Freestate Wellness, LLC]
* [https://www.gleaf.com/ Green Leaf Medical, LLC]
* [https://www.growwestmd.com/ Grow West MD, LLC]
* [https://www.harvestofmd.com/ Harvest of Maryland Cultivation, LLC]
* [http://www.hmshealthllc.com/ HMS Health, LLC]
* [https://www.holisticindustries.com/ Holistic Industries, Inc.]
* [https://kindtherapeuticsusa.com/ Kind Therapeutics USA, LLC]
* Maryland Compassionate Care and Wellness, LLC dba as Grassroots Cannabis
* [https://www.shorenaturalrx.com/ Shore Natural Rx, LLC]
* [https://www.sunmedgrowers.com/welcome SunMed Growers LLC]
* [https://ma.temescalwellness.com/ Temescal Wellness]
 
The state opened the application process again for growers and processors, with applications being accepted from March 25 to May 24, 2019. (Seeking to add four new growers and 10 new processors.) The state requires a $2,000 application fee<ref name="MMCCMedCannApp">{{cite web |url=https://mmcc.maryland.gov/Documents/03.25.2019%20MMCC%20Grower%20Application%20copy.pdf |format=PDF |title=Medical Cannabis Grower License Application |author=Maryland Medical Cannabis Commission |publisher=Government of Maryland |date=25 March 2019 |accessdate=27 April 2019}}</ref> and a $250,000 two-year license fee.<ref name="WheelerMedical14">{{cite web |url=https://www.baltimoresun.com/news/maryland/sun-investigates/bs-md-medical-marijuana-fees-20141011-story.html |title=Medical marijuana fees stir debate in Maryland |author=Wheeler, T.B. |work=The Baltimore Sun |date=11 October 2014 |accessdate=27 April 2019}}</ref>
 
 
'''Massachusetts''':
 
The state does not require vertical integration among its growers, dispensaries, and producers, but many growers may also be integrated with dispensaries, etc. Massachusetts currently has 10 licensed cultivators<ref name="CCCLicensing">{{cite web |url=https://mass-cannabis-control.com/licensing/ |title=Licensing |author=Cannabis Control Commission |publisher=Government of Massachusetts |accessdate=27 April 2019}}</ref>:
 
* [https://www.berkshireroots.com/ Berkshire Roots, Inc.]
* [https://www.cultivatemass.com/ Cultivate Holdings, LLC]
* [https://gardenremedies.com/ Garden Remedies, Inc.]
* [https://myinsa.com/ I.N.S.A., Inc.]
* [https://netacare.org/ New England Treatment Access, LLC]
* [https://nealternatives.com/ Northeast Alternatives, Inc.]
* [https://patriotcare.org/ Patriot Care Corp.]
* [https://www.revolutionaryclinics.org/ Revolutionary Clinics II, Inc.]
* [https://ma.sanctuarymed.com/ Sanctuary Medicinals, Inc.]
* [https://ma.temescalwellness.com/ Temescal Wellness of Massachusetts Holdings, LLC]
 
Application and license fees vary based on how many plants are to be grown in the cultivation facility. Refer to the Cannabis Control Commission's guidance document "[https://mass-cannabis-control.com/guidancedocuments/ Guidance for Application and License Fees]" for details.
 
 
'''Michigan''':
 
The state does not require vertical integration among its growers, dispensaries, and producers, but many growers may also be integrated with dispensaries, etc. Michigan currently has 21 licensed cultivators<ref name="DLRALicensing">{{cite web |url=https://www.michigan.gov/lara/0,4601,7-154-89334_79571_78089---,00.html |title=Medical Marijuana Facilities Licensing |author=Department of Licensing and Regulatory Affairs |publisher=Government of Michigan |accessdate=27 April 2019}}</ref>:
 
* 3843 Euclid, LLC
* A & H Partners, LLC
* Adams Family Farms, LLC
* Alvarez Cultivation, LLC
* Attitude Wellness, LLC
* BlueSol Biomedical, LLC
* Choice Labs, LLC
* DJR Michigan Properties, LLC dba High Level Health
* Exclusive Brands, LLC
* Free Reign, LLC
* Golden Harvests, LLC
* Great Lakes Cultivation, LLC
* Great Lakes Natural Remedies, Inc.
* Green Peak Industries, LLC
* [http://www.organilifegroup.com/ OrganiLife of Michigan, LLC]
* Pure Green, LLC
* [https://www.redbudroots.com/ Redbud Roots Lab III, LLC]
* R L Solutions, LLC dba Real Leaf Solutions
* SJS II, LLC
* VB Chesaning, LLC
* Vendco Michigan, Inc. dba Bigfoot Wellness
 
The state charges $6,000 for an application fee, as well as a "regulatory assessment" fee, which is not clear in cost (varies from $10,000 to $66,000).<ref name="DLRAWhatWill">{{cite web |url=https://www.michigan.gov/lara/0,4601,7-154-89334_79571_83746-453480--,00.html |title=What will the costs be for a license? |author=Department of Licensing and Regulatory Affairs |publisher=Government of Michigan |accessdate=27 April 2019}}</ref>
 
 
'''Minnesota''':
 
The state has chosen two companies to cultivate for its medical cannabis program<ref name="MDHMedicalCannManu">{{cite web |url=https://www.health.state.mn.us/people/cannabis/manufacture/index.html |title=Medical Cannabis Manufacturers/Laboratories |author=Minnesota Department of Health |publisher=Government of Minnesota |accessdate=27 April 2019}}</ref>:
 
* [http://www.leaflinelabs.com/ LeafLine Labs, LLC]
* [http://minnesotamedicalsolutions.com/ Minnesota Medical Solutions, LLC]
 
Further applications are not being accepted at this time. A $20,000 application fee was due for anyone who applied.<ref name="MDHMedicalCann">{{cite web |url=https://www.health.state.mn.us/people/cannabis/manufacture/selection/mfrqa.html |title=Medical Cannabis Manufacturer Selection Questions and Answers |author=Minnesota Department of Health |publisher=Government of Minnesota |accessdate=27 April 2019}}</ref>
 
 
'''Missouri''':
 
* Medical marijuana passed in November 2018; Missouri Department of Health and Senior Services is still sorting out the details.<ref name="MarsoMedical18">{{cite web |url=https://www.kansascity.com/living/health-fitness/article221302705.html |title=Medical marijuana in Missouri: When—and if—you can get it |author=Marso, A. |work=The Kansas City Star |date=16 November 2018 |accessdate=27 April 2019}}</ref> Businesses interested in cultivating in the state may reportedly begin applying on August 3, 2019. Licensing application fees will be $10,000.<ref name="HolmanSoWhat19">{{cite web |url=https://www.news-leader.com/story/news/local/ozarks/2019/04/15/medical-marijuana-pot-business-license-cannabis-weed-legal-missouri/3437432002/ |title=So what's on that application for medical pot businesses? 144 questions — and uncertainty |author=Holman, G.J. |work=Springfield News-Leader |date=15 April 2019 |accessdate=27 April 2019}}</ref>
 
 
'''Montana''':
 
The medical marijuana program in the state is in a bit of disarray. As Michigan-based New Leaf Cannabis Consulting puts it<ref name="LowryMontana18">{{cite web |url=https://www.newleafcannabisconsulting.com/alaska-blog/2018/12/9/montana-cannabis-licensing-assistance |title=Montana Cannabis Licensing Information |author=Lowry, S. |publisher=New Leaf Cannabis Consulting |date=11 December 2018 |accessdate=27 April 2019}}</ref>:
 
<blockquote>Voters re-approved medical cannabis in the state in Nov. 2016. Dispensaries were supposed to not open until June 2017, but a Montana court ruled that they may reopen immediately. Montana used to have an established medical cannabis dispensary program, but a court ruling upholding a severe state law dismantled the dispensaries, by limiting the maximum number of patients to 3; that portion of the law is now repealed. </blockquote>
 
As New Leaf also points out, the state hasn't made publicly available a list of licensed, operational dispensaries and cultivators operating under the new terms.<ref name="LowryMontana18" />
 
 
'''Nevada''':
 
The current number and details of the state's licensed cultivators are unknown. Per an inquiry and a form letter emailed from the Marijuana Enforcement Division of Nevada, "the state is only permitted to release information on open dispensaries," and does not release information on current licensed cultivators. However, a list of provisional certificates awarded in November 2014 can still be found [https://tax.nv.gov/uploadedFiles/dpbhnvgov/content/Reg/MedMarijuana/cultivationscoresrankings12-21-15.pdf on their site], though many of the names are redacted due to confidentiality laws in the state.
 
Licensing fees for cultivation facilities differ based on product. Recreational marijuana cultivation has an initial $30,000 licensing fee, with renewal costs at $10,000. Medical marijuana cultivation has an initial $3,000 license, with renewal costs at $1,000.<ref name="DoTMari">{{cite web |url=https://tax.nv.gov/MME/Marijuana_Establishments_-_Home/ |title=Marijuana Establishments |author=Department of Taxation |publisher=Government of Nevada |accessdate=27 April 2019}}</ref>
 
 
'''New Hampshire''':
 
The state vertically integrates cultivation and dispensation of medical cannabis into alternative treatment centers, with the state currently allowing for four locations run by three entities<ref name="DHHSAltern">{{cite web |url=https://www.dhhs.nh.gov/oos/tcp/alternative-treatment.htm |title=Alternative Treatment Centers |author=Department of Health and Human Services |publisher=Government of New Hampshire |accessdate=27 April 2019}}</ref>:
 
* [http://www.primeatc.com/ Prime Alternative Treatment Centers of NH, Inc.]
* [http://www.sanctuaryatc.org/ Sanctuary ATC]
* [http://www.temescalwellness.com/ Temescal Wellness, Inc.] (two locations)
 
The state doesn't appear to be accepting new applications, and it's not clear what fees applicants had to pay.
 
 
'''New Jersey''':
 
The state vertically integrates cultivation and dispensation of medical cannabis into alternative treatment centers, with the state currently allowing for six locations run by six entities<ref name="DHHSAltern">{{cite web |url=https://www.nj.gov/health/medicalmarijuana/alt-treatment-centers/ |title=Alternative Treatment Centers |author=Department of Health |publisher=Government of New Jersey |date=17 December 2018 |accessdate=27 April 2019}}</ref>:
 
* [http://www.breakwateratc.org/ Breakwater Alternative Treatment Center Corp.]
* [https://nj.curaleaf.com/ CuraLeaf NJ, Inc.]
* [http://www.ccfnj.org/ Compassionate Care Foundation, Inc.]
* [http://www.gardenstatedispensary.com/ Garden State Dispensary]
* [http://www.greenleafcompassion.com/ Greenleaf Compassion Center]
* [http://www.harmonydispensary.org/ Harmony Dispensary]
 
An application period occurred in July 2018 to grant six more licenses. In December 2018, six additional providers were invited to proceed with the application process, though in February 2019 five appeals were filed by rejected applicants and an existing alternative treatment center in regards to the selected six. Due to the litigation, it's not clear if and when those six providers will become fully licensed and operational.<ref name="DHHSUpdateOn">{{cite web |url=https://www.nj.gov/health/medicalmarijuana/alt-treatment-centers/applications.shtml |title=Update on Expansion of Medicinal Marijuana Program |author=Department of Health |publisher=Government of New Jersey |date=17 December 2018 |accessdate=27 April 2019}}</ref><ref name="LivioTheseWeed19">{{cite web |url=https://www.nj.com/marijuana/2019/02/these-weed-growers-didnt-get-picked-to-grow-medical-marijuana-in-nj-now-they-are-ready-for-a-fight.html |title=These weed growers didn’t get picked to grow medical marijuana in N.J. Now they are ready for a fight |author=Livio, S.K.; Guion, P. |work=NJ.com |date=1 February 2019 |accessdate=27 April 2019}}</ref>
 
 
'''New Mexico''':
 
New Mexico vertically integrates cultivation and distribution. The state calls such licensed entities "licensed non-profit producers" (LNPPs), of which 91 locations are operational.<ref name="NMDOHLicensed19">{{cite web |url=https://nmhealth.org/publication/view/general/2101/ |title=Licensed Nonprofit Producers |author=Department of Health |publisher=Government of New Mexico |date=18 April 2019 |accessdate=27 April 2019}}</ref> (Go [https://nmhealth.org/publication/view/general/2101/ here] to see the full list.)
 
The state is not accepting additional applications at this time. Initial application fee was $10,000, with a license fee of "thirty thousand dollars ($30,000) for the first 150 cannabis plants to be possessed by the non-profit producer, and ten thousand dollars ($10,000) for each additional quantity of 50 plants thereafter to be possessed, up to a maximum collective total of 450 cannabis plants."<ref name="NMAC7.34.4">{{cite web |url=https://nmhealth.org/resource/view/222/ |title=7.34.4 Health - Medical Use of Cannabis - Licensing Requirements for Producers, Couriers, Manufacturers, and Laboratories |publisher=Government of New Mexico |accessdate=27 April 2019}}</ref>
 
 
'''New York''':
 
The state vertically integrates cultivation and dispensation of medical cannabis into registered organizations. Each registered organization can have one cultivation facility and up to four dispensaries. Those organizations are<ref name="NYSDoHRegistered19">{{cite web |url=https://www.health.ny.gov/regulations/medical_marijuana/application/selected_applicants.htm |title=Registered Organization Locations |author=Department of Health |publisher=Government of New York State |date=April 2019 |accessdate=27 April 2019}}</ref>:
 
* [http://col-careny.com/ Columbia Care NY, LLC]
* [http://etainhealth.com/ Etain, LLC]
* [https://medmen.com/ny/ MedMen, Inc.]
* [https://www.shopbotanist.com/ NYCANNA, LLC dba The Botanist or Acreage NY]
* [https://ny.curaleaf.com/ PalliaTech NY, LLC dba CuraLead]
* [http://www.pharmacannis.com/ny PharmaCann, LLC]
* [http://vireohealthny.com/ Vireo Health of New York, LLC]
* [https://citiva.com/ Citiva Medical, LLC]
* [http://fpnys.com/ Fiorello Pharmaceuticals, Inc. dba FP Wellness]
* [http://valleyagriceuticals.com/ Valley Agriceuticals, LLC dba Remedy-NY]
 
Applications are not currently being accepted. Applications fee was $10,000, licensing fee $200,000.<ref name="NYSDoHMedical18">{{cite web |url=https://www.health.ny.gov/regulations/medical_marijuana/application/applications.htm |title=Medical Marijuana Program Applications |author=Department of Health |publisher=Government of New York State |date=April 2018 |accessdate=27 April 2019}}</ref>
 
 
'''North Dakota''':
 
The state approved two cultivation sites in 2018 for its medical marijuana program<ref name="NDDoHMedical18">{{cite web |url=https://www.ndhealth.gov/mm/PDF/Press_Releases/2018-5-16_Medical_Marijuana_Review_Panel_Selects_Manufacturing_Facilities.pdf |format=PDF |title=Medical Marijuana Application Review Panel Selects Two Manufacturing Facilities |author=Department of Health |publisher=Government of North Dakota |date=16 May 2018 |accessdate=27 April 2019}}</ref>:
 
* [https://www.grassrootscannabis.com/ GR Vending ND, LLC dba Grassroots Cannabis]
* [https://www.puredakotand.com/ Pure Dakota, LLC]
 
Additional cultivation applications don't appear to be accepted. An initial $5,000 application fee was required, and a $110,000 certification fee for a two-year license.<ref name="NDDoHFreq18">{{cite web |url=http://www.ndhealth.gov/mm/pdf/program_informational_guides/faq%20for%20compassion%20centers%20-%20updated%203-1-2018.pdf |format=PDF |title=Frequently Asked Questions – Manufacturing Facilities and Dispensaries |author=Department of Health |publisher=Government of North Dakota |date=28 Febrary 2018 |accessdate=27 April 2019}}</ref>
 
 
'''Ohio''':
 
Agri-Med Ohio, LLC
[https://ancientrootsohio.com/ Ancient Roots, LLC]
Ascension BioMedical, LLC
AT-CPC of Ohio, LLC
[http://www.buckeyerelief.com/ Buckeye Relief, LLC]
Certified Cultivators
[https://col-careoh.com/ Columbia Care OH, LLC]
[https://www.crescolabs.com/ Cresco Labs Ohio, LLC]
Farkas Farms, LLC
Fire Rock Ltd.
FN Group Holdings, LLC
Galenas, LLC
Greenleaf Gardens
[http://growohio.com/ Grow Ohio Pharmaceuticals, LLC]
Harvest Grows, LLC
Hemma, LLC
Mother Grows Best, LLC
OhiGrow, LLC
Ohio Clean Leaf, LLC
[https://www.ohiogrowntherapies.com/ Ohio Grown Therapies, LLC]
OPC Cultivation, LLC
Paragon Development Group, LLC
Parma Wellness Center, LLC
PharmaCann Ohio, LLC
Pure OH, LLC
[http://pureohiowellness.com/ Pure Ohio Wellness, LLC]
Riviera Creek Holdings, LLC
[https://standardwellness.com/ Standard Wellness Company, LLC]
Terradiol Ohio, LLC (may get revoked<ref name="ByerCanton18">{{cite web |url=https://www.ohio.com/news/20181221/canton-cannabis-growers-in-jeopardy-of-losing-licenses/1 |title=Canton cannabis growers in jeopardy of losing licenses |author=Byer, K. |work=Akron Beacon Journal |date=21 December 2018 |accessdate=27 April 2019}}</ref>
 
 
'''Oklahoma''':
 
In April 2019, the state released a document containing 118 ''pages'' of cannabis cultivators for its medical marijuana program. Consult the "[http://omma.ok.gov/list-of-businesses List of Licensed Businesses]" to view the entire list. Application/license fee is $2,500 annually.<ref name="OMMABusiness">{{cite web |url=http://omma.ok.gov/business-application-information3 |title=Business Application Information |author=Oklahoma Medical Marijuana Authority |publisher=Government of Oklahoma |accessdate=27 April 2019}}</ref>
 
 
'''Oregon'''
 
 
 
 
'''Pennsylvania''':
 
 
 
'''Rhode Island''':
 
 
 
 
'''Utah''':
 
* Medical marijuana passed in November 2018; the state is still working on laboratory testing terms<ref name="USLUtahMedical18">{{cite web |url=https://le.utah.gov/interim/2018/pdf/00004612.pdf |format=PDF |title=Utah Medical Cannabis Act Overview |author=Utah State Legislature |publisher=State of Utah |date=14 November 2018 |accessdate=29 November 2018}}</ref>
 
 
'''Vermont''':
 
 
 
 
'''Washington''':
 
 
 
 
'''West Virginia''':
 
* Still working on developing its medical cannabis program.<ref name="BPHOffice">{{cite web |url=https://dhhr.wv.gov/bph/Pages/Medical-Cannabis-Program.aspx |title=Office of Medical Cannabis |work=Bureau for Public Health |publisher=State of West Virginia |accessdate=29 November 2018}}</ref> Draft legislation says the Bureau for Public Health will be responsible for approving testing laboratories.<ref name="BPHTitle64_17">{{cite web |url=http://dhhr.wv.gov/bph/Documents/MedicalCannabis/Proposed%20Rules/Medical%20Cannabis%20Program%20-%20Laboratories%20-%2064%20CSR%20111%20v1.pdf |format=PDF |title=Title 64, Legislative Rule, Bureau for Public Health, Series 111, Medical Cannabis Program - Laboratories |author=Bureau for Public Health |publisher=State of West Virginia |date=14 December 2017 |accessdate=29 November 2018}}</ref>
 
==References==
{{Reflist|colwidth=30em}}

Revision as of 21:23, 19 September 2019

Sandbox begins below

2. Sample Management

Regulation, Specification, or Guidance Requirement
ASTM E1578-18 C-2-1
EPA ERLN Laboratory Requirements 4.11.14
2.1 The system shall record and maintain the chain of custody for the laboratory's standards and reagents.
ASTM E1578-18 C-2-2
EPA ERLN Laboratory Requirements 4.11.14
2.2 The system shall record the current and historical storage location for the laboratory's standards and reagents.
ASTM E1578-18 C-2-3
EPA ERLN Laboratory Requirements 4.11.14
2.3 The system shall allow the laboratory's previously standardized standards and reagents to be assigned a new standard value.
ASTM E1578-18 C-2-4
EPA ERLN Laboratory Requirements 4.11.14
2.4 The system shall require the recording of a standard and reagent's first opening date.
ASTM E1578-18 C-2-5
EPA ERLN Laboratory Requirements 4.11.14
2.5 The system shall allow only active standards and reagents to be shown as available for use.
ASTM E1578-18 C-2-6
EPA ERLN Laboratory Requirements 4.11.14
2.6 The system shall allow standards and reagents to be flagged as no longer available for use by authorized personnel.
ASTM E1578-18 C-2-7 2.7 The system shall allow logically associated samples to be grouped together based on associated metadata such as sample type, test method, assigned user, and status.
ASTM E1578-18 C-2-8
EPA ERLN Laboratory Requirements 3.2
ISO/IEC 17025:2017 7.4.2
2.8 The system should allow for the accurate identification of a physical sample in the system via barcode or RFID technology.

7 CFR Part 331.17
9 CFR Part 121.17
21 CFR Part 211.84
42 CFR Part 73.17
ASTM E1492-11 4.2.1
ASTM E1578-18 C-2-9

2.9 The system should provide a means to manually or automatically track sample inventory amounts and status.
ASCLD/LAB Supp. Reqs. for the Accreditation of Forensic Science Testing Laboratories 5.9.1.1
ASTM E1578-18 C-2-10
2.10 The system shall be able to link test methods and specifications to standards and reagents.

21 CFR Part 211.84
21 CFR Part 211.166–7
21 CFR Part 211.194 (e)
21 CFR Part 212.40 (c)
21 CFR Part 212.61
21 CFR Part 212.70 (e)
21 CFR Part 225.58
21 CFR Part 226.58
21 CFR Part 606.65 (c)
21 CFR Part 606.151
ASTM E1578-18 C-2-11
EPA ERLN Laboratory Requirements 3.1.2.1
EPA ERLN Laboratory Requirements 4.3.2
EPA ERLN Laboratory Requirements 4.11.3.2
EPA QA/G-5 2.2.5
USDA Administrative Procedures for the PDP 8.5
WHO Technical Report Series, #986, Annex 2, 17.7
WHO Technical Report Series, #986, Annex 2, 17.22–25

2.11 The system shall allow samples and tests to be created and used specifically for capturing data related to unique forms of sampling and testing such as representative sampling, calibration testing, quality control testing, preventative maintenance testing, stability testing, sterility testing, compatibility testing, identity testing, proficiency testing, and service-event-related testing.

3. Core Laboratory Testing and Experiments

Regulation, Specification, or Guidance Requirement

21 CFR Part 211.84 (d)
ASCLD/LAB Supp. Reqs. for the Accreditation of Forensic Science Testing Laboratories 5.1.3.1
ASTM E1578-18 C-3-1
ISO 15189:2012 5.3.2.7

3.1 The system shall be able to record the identity of any standards and reagents used in laboratory testing, as well as for each sample or test during result entry. Linked to their identity should also be manufacturer and supplier information (such as certificates of testing); lot numbers; reception, preparation, and expiry dates; name of preparer; reliability testing results; and approval for use.
21 CFR Part 211.84 (e)
42 CFR Part 493.1252 (d)
ASTM E1578-18 C-3-2
3.2 The system shall allow users to only select approved, non-expired standards and reagents for tests and experiments.
42 CFR Part 493.1252 (d)
ASTM E1578-18 C-3-3
3.3 The system shall prevent standards, reagents, and other media from being used in testing if they would expire during the testing.
ASTM E1578-18 C-3-4 3.4 The system shall be able to check physical, control, and specification limits for an instrument sample.
ASTM E1578-18 C-3-6 3.5 The system should allow result entry for all tests linked to a single sample, as well as for multiple samples linked to a single test.
ASTM E1578-18 C-3-7 3.6 The system should allow user-definable result entry methods, e.g., uploading from a spreadsheet.
ASTM E1578-18 C-3-8 3.7 The system should allow outsourced samples to be tracked for aliquoting, chain-of-custody, results entry, and approval purposes.
ASTM E1578-18 C-3-9 3.8 The system shall allow the creation and assignment of retest workflow, while allowing the system or assigned user to determine the existence of a retesting due date and whether or not a new sample is required for the retest.
ASTM E1578-18 C-3-10 3.9 The system shall support, at a minimum, the floating point/real number, integer number, text, date, list, file, calculated, Boolean, and interval test result data types, allowing users to define the data type for specific test results.
AIHA-LAP Policies 2018 2A.7.8.2
ASTM E1578-18 C-3-11
3.10 The system shall allow users to enter operators such as <, >, +, and - with numeric test results.
ASTM E1578-18 C-3-12 3.11 The system should allow inter- and intra-assay calculations to be performed, including the use of advanced math functions.
42 CFR Part 493.1241
ASTM E1578-18 C-3-13
EPA ERLN Laboratory Requirements 4.9.11
3.12 The system should effectively alert users upon entry of out-of-specification test results.

21 CFR Part 211.194
21 CFR Part 212.60 (g)
21 CFR Part 606.160
ASTM E1578-18 C-3-14
EPA ERLN Laboratory Requirements 3.1.2.3–4
EPA ERLN Laboratory Requirements 3.2
EPA ERLN Laboratory Requirements 4.3.4
EPA ERLN Laboratory Requirements 4.8.1–4
EPA ERLN Laboratory Requirements 4.11.16
USDA Data and Instrumentation for PDP 5.4.2
USDA Data and Instrumentation for PDP 8.1.3
WHO Technical Report Series, #986, Annex 2, 15.8

3.13 The system shall be able to record a complete record of all data created in the course of a test or experiment, including instruments used, calculations performed, and associated graphs, charts, and spectra. The record should also be able to capture the signatures of those who performed the test or experiment, as well as those who reviewed the record for compliance purposes.