Chromatography data system

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Sometimes referred to as a chromatography data system (CDS), a chromatography data management system (CDMS) is a set of dedicated data-collection tools that interface and/or integrate with a laboratory's chromatography equipment.


History of the CDMS

The first attempts to automate the analysis of chromatography data through electronics took place in the early 1970s. These analysis tools utilized microprocessor-based integrators, "dedicated devices for measuring chromatographic peaks and performing user-specified calculations" which also featured a printer plotter to output the results. [1] Limited memory plagued those early systems, preventing more than one chromatograph from being stored at any one time. This became less of problem for large labs with bigger budgets in the mid-70s, as expensive centralized data systems were installed, allowing greater data storage and sharing capabilities.[1]

As computers shrank in size, the personal computer became a viable reality. In 1980 entrepreneur and Hewlett-Packard prodigy Dave Nelson saw the potential the personal computer could have on the field of analytical chemistry, joining with partner Harmon Brown to create Nelson Analytical Inc. That year they developed the first CDMS personal computer software, soon followed by Turbochrom, the first CDMS system for MS Windows.[2][3] This innovation quickly spread from analytical chemistry labs to the fields of environmental, forensic, and pharmaceutical sciences. At the same time chromatography minicomputers like Hewlett-Packard's 3350 LAS Lab Automation System and Perkin-Elmer's LIMS 2000 CLAS chromatography laboratory automation system were seeing increased utilization, featuring the data acquisition and processing of up to 32 or more simultaneous chromatographs.[4]

In the 1990s, more affordable higher-performance PCs — combined with tighter networking standards — allowed for networks of CDMSs, especially those installed on personal computers. By the late '90s, the CDMS commonly featured the ability to set up a methodology and analytical run information, control some instruments, acquire injection data, process the data in different ways, save the data, and transmit it to other systems like a LIMS. [1]

References

Further reading