Difference between revisions of "Template:Article of the week"

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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig2 Backman BMCBio2016 17.gif|240px]]</div>
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'''"[[Journal:systemPipeR: NGS workflow and report generation environment|systemPipeR: NGS workflow and report generation environment]]"'''
'''"[[Journal:Data to diagnosis in global health: A 3P approach|Data to diagnosis in global health: A 3P approach]]"'''


Next-generation sequencing (NGS) has revolutionized how research is carried out in many areas of biology and medicine. However, the analysis of NGS data remains a major obstacle to the efficient utilization of the technology, as it requires complex multi-step processing of big data, demanding considerable computational expertise from users. While substantial effort has been invested on the development of software dedicated to the individual analysis steps of NGS experiments, insufficient resources are currently available for integrating the individual software components within the widely used R/Bioconductor environment into automated [[Workflow|workflows]] capable of running the analysis of most types of NGS applications from start-to-finish in a time-efficient and reproducible manner. ('''[[Journal:systemPipeR: NGS workflow and report generation environment|Full article...]]''')<br />
With connected medical devices fast becoming ubiquitous in healthcare monitoring, there is a deluge of data coming from multiple body-attached sensors. Transforming this flood of data into effective and efficient diagnosis is a major challenge. To address this challenge, we present a "3P" approach: personalized patient monitoring, precision diagnostics, and preventive criticality alerts. In a collaborative work with doctors, we present the design, development, and testing of a healthcare data analytics and communication framework that we call RASPRO (Rapid Active Summarization for effective PROgnosis). The heart of RASPRO is "physician assist filters" (PAF) that 1. transform unwieldy multi-sensor time series data into summarized patient/disease-specific trends in steps of progressive precision as demanded by the doctor for a patient’s personalized condition, and 2. help in identifying and subsequently predictively alerting the onset of critical conditions. ('''[[Journal:Data to diagnosis in global health: A 3P approach|Full article...]]''')<br />
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Revision as of 15:25, 18 March 2019

Fig9 Pathinarupothi BMCMedInfoDecMak2018 18.png

"Data to diagnosis in global health: A 3P approach"

With connected medical devices fast becoming ubiquitous in healthcare monitoring, there is a deluge of data coming from multiple body-attached sensors. Transforming this flood of data into effective and efficient diagnosis is a major challenge. To address this challenge, we present a "3P" approach: personalized patient monitoring, precision diagnostics, and preventive criticality alerts. In a collaborative work with doctors, we present the design, development, and testing of a healthcare data analytics and communication framework that we call RASPRO (Rapid Active Summarization for effective PROgnosis). The heart of RASPRO is "physician assist filters" (PAF) that 1. transform unwieldy multi-sensor time series data into summarized patient/disease-specific trends in steps of progressive precision as demanded by the doctor for a patient’s personalized condition, and 2. help in identifying and subsequently predictively alerting the onset of critical conditions. (Full article...)

Recently featured:

▪ Building a newborn screening information management system from theory to practice
▪ Adapting data management education to support clinical research projects in an academic medical center
▪ Development of an electronic information system for the management of laboratory data of tuberculosis and atypical mycobacteria at the Pasteur Institute in Côte d’Ivoire
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