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"Ten simple rules for developing usable software in computational biology"

The rise of high-throughput technologies in molecular biology has led to a massive amount of publicly available data. While computational method development has been a cornerstone of biomedical research for decades, the rapid technological progress in the wet laboratory makes it difficult for software development to keep pace. Wet lab scientists rely heavily on computational methods, especially since more research is now performed in silico. However, suitable tools do not always exist, and not everyone has the skills to write complex software. Computational biologists are required to close this gap, but they often lack formal training in software engineering. To alleviate this, several related challenges have been previously addressed in the Ten Simple Rules series, including reproducibility, effectiveness, and open-source development of software. (Full article...)

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