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| <div class="nonumtoc">__TOC__</div>
| | ==This is demo code demoing math== |
| {{ombox
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| | type = notice
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| | style = width: 960px;
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| | text = This is sublevel2 of my sandbox, where I play with features and test MediaWiki code. If you wish to leave a comment for me, please see [[User_talk:Shawndouglas|my discussion page]] instead.<p></p>
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| }}
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| ==Sandbox begins below==
| | As a typical example, from a [[calibration plot]] following a [[linear equation]] taken here as the simplest possible model: |
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| ==AB Sciex Pte. Ltd.== | | : <math>f(x) = ax + b </math> |
| '''Main landing page for cannabis testing''': https://sciex.com/applications/food-and-beverage-testing/cannabis-testing
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| Commonly known as Sciex, AB Sciex Pte. Ltd. develops "solutions in mass spectrometry paired with capillary electrophoresis and liquid chromatography."<ref name="SciexAbout">{{cite web |url=https://sciex.com/about-us |title=About Us |publisher=AB Sciex Pte. Ltd |accessdate=20 November 2018}}</ref> The company markets some of its solutions for cannabis lab testing, including<ref name="SciexCanna">{{cite web |url=https://sciex.com/applications/food-and-beverage-testing/cannabis-testing |title=Grow Your Cannabis Lab's Potential and Bottom Line with LC-MS/MS Analysis |publisher=AB Sciex Pte. Ltd |accessdate=20 November 2018}}</ref>:
| | where, <math>f(x)</math> corresponds to the signal measured (e.g. voltage, luminescence, energy, etc.) |
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| * potency testing
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| * mycotoxin testing
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| * pesticide testing
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| * terpenes testing
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| ===Instruments and methods===
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| ====Triple Quad systems====
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| Sciex offers four different Triple Quad systems for tandem mass spectrometry paired with liquid chromatography (LC-MS/MS): the 6500+, 5500, 4500, and 3500. The company claims that with these systems "scientists can acquire multiple reaction monitoring (MRM), precursor, neutral loss, and product ion scans to develop powerful methods for complex matrices, all while maintaining reproducibility and robustness."<ref name="SciexTQ">{{cite web |url=https://sciex.com/products/mass-spectrometers/triple-quad-systems |title=Triple Quad LC-MS/MS Systems |publisher=AB Sciex Pte. Ltd |accessdate=21 November 2018}}</ref>
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| * [https://sciex.com/products/mass-spectrometers/triple-quad-systems/triple-quad-6500plus-system 6500+]
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| * [https://sciex.com/products/mass-spectrometers/triple-quad-systems/triple-quad-5500-system 5500]
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| * [https://sciex.com/products/mass-spectrometers/triple-quad-systems/triple-quad-4500-system 4500]
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| * [https://sciex.com/products/mass-spectrometers/triple-quad-systems/triple-quad-3500-system 3500]
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| ====QTRAP systems====
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| Sciex also offers three different Triple Quad Linear Ion Traps (QTRAP) systems for LC-MS/MS: the 6500+, 5500, and 4500. The company states that these are similar to the Triple Quad systems "but with enhanced scan functions to enable simultaneous quantitation and confirmation."<ref name="SciexQTRAP">{{cite web |url=https://sciex.com/products/mass-spectrometers/qtrap-systems |title=QTRAP LC-MS/MS Systems |publisher=AB Sciex Pte. Ltd |accessdate=21 November 2018}}</ref>
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| * [https://sciex.com/products/mass-spectrometers/qtrap-systems/qtrap-6500plus-system QTRAP 6500+]
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| * [https://sciex.com/products/mass-spectrometers/qtrap-systems/qtrap-5500-system QTRAP 5500]
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| * [https://sciex.com/products/mass-spectrometers/qtrap-systems/qtrap-4500-system QTRAP 4500]
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| ====vMethod for Cannabis====
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| Sciex also offers a "[https://sciex.com/products/methods/vmethod-application-for-quantitation-of-pesticide-residues-and-cannabinoids-in-cannabis-matrices-10 vMethod]," a quantitation method for pesticide and cannabinoid analysis, that works on many of their LC-MS/MS systems.<ref name="SciexVMethodCann">{{cite web |url=https://sciex.com/products/methods/vmethod-application-for-quantitation-of-pesticide-residues-and-cannabinoids-in-cannabis-matrices-10 |title=vMethod Application for Quantitation of Pesticide Residues and Cannabinoids in Cannabis Matrices 1.0 |publisher=AB Sciex Pte. Ltd |accessdate=21 November 2018}}</ref>
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| ==Agilent Technologies, Inc.==
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| '''Main landing page for cannabis testing''': https://www.agilent.com/en/promotions/cannabis
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| [[Agilent Technologies, Inc.]] is an instrument and software development company for the life sciences, diagnostics, and applied chemical industries. The company offers a variety of chromatography and spectrometry instruments (using a wide array of techniques) and software for the cannabis testing industry, including<ref name="AgilentCanna">{{cite web |url=https://www.agilent.com/en/promotions/cannabis |title=Cannabis Testing Solutions |publisher=Agilent Technologies, Inc |accessdate=21 November 2018}}</ref>:
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| * potency and efficacy testing
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| * heavy metals testing
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| * pesticide testing
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| * residual solvents testing
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| * terpenes testing
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| ===Instruments and methods===
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| The company suggests instrument options based on what type of testing will occur.<ref name="AgilentCanna" />
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| ====Potency and efficacy testing====
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| * [https://www.agilent.com/en/products/liquid-chromatography/infinitylab-lc-workflow-solutions/infinitylab-sfc-solutions/1260-infinity-ii-sfc-system 1260 Infinity II SFC System]: a supercritical fluid chromatography (SFC) system with an ultra-high performance liquid chromatography (UHPLC) power range
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| * [https://www.agilent.com/en/products/liquid-chromatography/infinitylab-analytical-lc-solutions/1290-infinity-ii-lc-systems/1290-infinity-ii-lc-system 1290 Infinity II LC System]: an UHPLC system
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| * [https://www.agilent.com/en/products/liquid-chromatography/infinitylab-lc-workflow-solutions/infinitylab-2d-lc-solutions/1290-infinity-ii-2d-lc-system 1290 Infinity II 2D-LC System]: similar to the prior, but with two-dimensional liquid chromatography
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| * [https://www.agilent.com/en/products/mass-spectrometry/gc-ms-instruments/5977b-gc-msd 5977B GC/MSD]: a single-quadrupole GC/MS system with an electron ionization (EI) source
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| * [https://www.agilent.com/en/products/ftir/ftir-benchtop-systems/cary-630-ftir-spectrometer Cary 630 FTIR Spectrometer]: portable fourier-transform infrared (FTIR) spectroscopy
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| * [https://www.agilent.com/en/products/gas-chromatography/gc-systems/intuvo-9000-gc-system Intuvo 9000 GC System]: an ultra-fast gas chromatography system
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| ====Heavy metals testing====
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| * [https://www.agilent.com/en/products/icp-oes/icp-oes-instruments/5110-icp-oes-instruments 5110 ICP-OES Instrument]: an inductively coupled plasma optical emission spectrometry (ICP-OES) instrument with synchronous radial and axial measurement
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| * [https://www.agilent.com/en/products/icp-ms/icp-ms-systems/7800-icp-ms 7800 ICP-MS]: an inductively coupled plasma mass spectrometry (ICP-MS) instrument
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| * [https://www.agilent.com/en/products/icp-ms/icp-ms-systems/7900-icp-ms 7900 ICP-MS]: an inductively coupled plasma mass spectrometry (ICP-MS) instrument with higher matrix tolerance, wider dynamic range, and better signal-to-noise ratio
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| * [https://www.agilent.com/en/products/icp-ms/icp-ms-systems/8900-triple-quadrupole-icp-ms 8900 Triple Quadrupole ICP-MS]: an inductively coupled plasma normal and tandem mass spectroscopy instrument with triple quadrupole
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| ====Pesticide testing====
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| * [https://www.agilent.com/en/products/mass-spectrometry/lc-ms-instruments/triple-quadrupole-lc-ms 6400 Triple Quadrupole LC/MS]: liquid chromatography normal and tandem mass spectrometry instruments, with four variations (6420A, -60C, -70A, and 95B)
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| * [https://www.agilent.com/en/products/mass-spectrometry/lc-ms-instruments/quadrupole-time-of-flight-lc-ms/6500-series-accurate-mass-quadrupole-time-of-flight-(q-tof)-lc-ms 6500 Series Accurate-Mass Quadrupole Time-of-Flight (Q-TOF) LC/MS]: quadrupole time-of-flight liquid chromatography-mass spectrometry instruments, with five variations (6530, -45, -45XT, -50, and -60)
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| * [https://www.agilent.com/en/products/mass-spectrometry/gc-ms-instruments/7000d-triple-quadrupole-gc-ms 7000D Triple Quadrupole GC/MS]: a gas chromatography normal and tandem mass spectroscopy instrument with triple quadrupole and dynamic MRM
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| * [https://www.agilent.com/en/products/mass-spectrometry/analyzers-databases-libraries/food/gc-ms-ms-pesticides-analyzer GC/MS/MS Pesticides Analyzer]: a gas chromatography tandem mass spectroscopy instrument with triple quadrupole
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| ====Residual solvents testing====
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| * [https://www.agilent.com/en/products/gas-chromatography/gc-systems/7890b-gc-system 7890 Series GC with 7697A Headspace Sampler and Flame Ionization Detector]: a gas chromatography instrument combined with the [https://www.agilent.com/en/products/gas-chromatography/sample-preparation-introduction/7697a-headspace-sampler 7697A Headspace Sampler] and [https://www.agilent.com/store/en_US/Prod-G3431-60531/G3431-60531 compatible flame ionization detector]
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| ====Terpenes====
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| * [https://www.agilent.com/en/products/liquid-chromatography/infinitylab-lc-series-modules/lc-detectors/1260-infinity-ii-diode-array-detector-hs 1260 Infinity II Diode Array Detector HS]: a liquid chromatography high-sensitivity diode array detector
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| * [https://www.agilent.com/en/products/liquid-chromatography/infinitylab-lc-series-modules/lc-detectors/1260-infinity-ii-diode-array-detector-wr 1260 Infinity II Diode Array Detector WR]: a liquid chromatography wide-range diode array detector
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| * [https://www.agilent.com/en/products/gas-chromatography/gc-systems/7890b-gc-system 7890 Series GC]: a gas chromatography instrument
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| * [https://www.agilent.com/en/products/gas-chromatography/gc-systems/intuvo-9000-gc-system Intuvo 9000 GC System]: an ultra-fast gas chromatography system
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| ===Software===
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| * [https://www.agilent.com/en/products/software-informatics/atomic-spectroscopy-data-systems/icp-expert-software-for-icp-oes ICP Expert Software for ICP-OES]: inductively coupled plasma optical emission spectrometry (ICP-OES) software for data analysis
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| * [https://www.agilent.com/en/products/software-informatics/masshunter-suite/masshunter MassHunter]: mass spectrometry software for instrument control, monitoring, and data analysis
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| * [https://www.agilent.com/en/products/software-informatics/molecular-spectroscopy-data-systems/ftir-software/microlab-ftir-software MicroLab]: fourier-transform infrared spectroscopy software for quantitative method development, calibrations, and data analysis
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| ==BÜCHI Labortechnik AG==
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| '''Main landing page for cannabis production''': https://www.buchi.com/en/cannabis-application-booklet
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| BÜCHI Labortechnik AG is laboratory technology development company for research and development, quality control, and production operations globally. The company offers a variety of instruments and equipment for cannabis production workflow, including<ref name="BUCHICanna">{{cite web |url=https://static1.buchi.com/sites/default/files/content-page/downloads/Application_Booklet_Cannabis_.pdf |format=PDF |title=Cannabis Booklet: Theory & Applications |publisher=BÜCHI Labortechnik AG |accessdate=21 November 2018}}</ref>:
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| * post-chromatography and post-extraction solvent concentration
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| * preperative chromatography for purification of cannabinoids
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| * microencapsulation of CBD into gelatin beads/soft oil core capsules
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| * formulation of CBD into an inhalable/edible dry powder
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| See the Theory & Applications booklet (main landing page) for more details on how to integrate the equipment for each activity.
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| ===Instruments and methods===
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| The company suggests instrument options based on what type of production activity will occur.<ref name="BUCHICanna" />
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| ===Post-chromatography and post-extraction solvent concentration===
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| * [https://www.buchi.com/us-en/products/industrial-evaporation/rotavapor-r-220-pro Rotavapor R-220 Pro]: an industrial evaporator with programmable methods, automatic distillation, and remote monitoring options
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| * [https://www.buchi.com/us-en/products/industrial-evaporation/recirculating-chiller-f-325 F-325 Recirculating Chiller]
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| * [https://www.buchi.com/us-en/products/laboratory-evaporation/vacuum-pump-v-600 V-600 Vacuum Pump]
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| ===Preparative chromatography for purification of cannabinoids===
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| * [https://www.buchi.com/us-en/products/preparative-chromatography/reveleris-x2 Reveleris X2]: flash column chromatography for separations and flash purification; more advanced than the Sepacore
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| * [https://www.buchi.com/us-en/products/preparative-chromatography/sepacore-flash-systems-x10-x50 Sepacore Flash Systems X10/X50]: flash column chromatography for separations and flash purification
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| * [https://www.buchi.com/us-en/products/preparative-chromatography/pump-module-c-601-c-605 C-601 Pump]
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| * [https://www.buchi.com/us-en/products/preparative-chromatography/els-detector-c-650 C-650 ELS Detector]: an evaporative light scattering detector for any mobile phase or gradient
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| ===Microencapsulation of CBD into gelatin beads/soft oil core capsules===
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| * [https://www.buchi.com/us-en/products/spray-drying-and-encapsulation/encapsulator-b-390 Encapsulator B-390]
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| * [https://www.buchi.com/us-en/products/spray-drying-and-encapsulation/encapsulator-b-395-pro Encapsulator B-395 Pro]
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| * [https://www.buchi.com/us-en/products/laboratory-evaporation/rotavapor-r-300 Rotavapor R-300]: a rotary evaporator
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| * [https://www.buchi.com/us-en/products/laboratory-evaporation/interface-i-300-pro Interface I-300 Pro]
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| * [https://www.buchi.com/us-en/products/laboratory-evaporation/recirculating-chiller-f-305-f-308-f-314 F-305 Recirculating Chiller]
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| * [https://www.buchi.com/us-en/products/laboratory-evaporation/vacuum-pump-v-300 V-300 Vacuum Pump]
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| ===Formulation of CBD into an inhalable/edible dry powder===
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| * [https://www.buchi.com/us-en/products/spray-drying-and-encapsulation/mini-spray-dryer-b-290 B-290 Mini Spray Dryer]
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| * [https://www.buchi.com/us-en/products/spray-drying-and-encapsulation/inert-loop-b-295 B-295 Inert Loop]
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| ==CEM Corporation==
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| '''Main landing page for cannabis testing''': http://cem.com/cannabis
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| CEM Corporation is laboratory instrumentation and method design and development company, with a focus on compositional analysis of food and other samples, as well acid digestion and chemical synthesis. CEM specifically offers two different instruments for cannabis testing and analysis labs, including instruments for the<ref name="CEMCanna">{{cite web |url=http://cem.com/cannabis |title=Cannabis Analysis |publisher=CEM Corporation |accessdate=21 November 2018}}</ref>:
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| * extraction for potency, pesticide, terpene, and mycotoxin testing
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| * microwave digestion of oils, edibles, and plant material (before, e.g., inductively coupled plasma mass spectroscopy)
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| ===Instruments and methods===
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| * [http://cem.com/edge/ EDGE]: an automated instrument for energized dispersive extraction and dispersive solid-phase extraction (dSPE)
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| * [http://cem.com/mars-6/ MARS 6]: a microwave digestion system with hundreds of preprogrammed methods
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| ==References==
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| {{Reflist|colwidth=30em}}
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