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In the field of bioengineering, biofunctionalisation (or biofunctionalization) is the modification of a material to have biological function and/or stimulus, whether permanent or temporary, while at the same time being biologically compatible.[1][2][3]

Various types of medical implants are designed to biofunctionalize so that they can replace or repair a defective biological function [4] and are accepted by the host organism.[5][6]


  1. ^ Gübitz G, Nyanhongo GS, Walter S (2011). Biofunctionalization of Polymers and their Applications (Advances in Biochemical Engineering Biotechnology). Berlin: Springer. ISBN 978-3-642-21948-1.
  2. ^ Kumar CSSR (2006). Biofunctionalization of Nanomaterials (Nanotechnologies for the Life Sciences). Chichester: John Wiley & Sons. ISBN 3-527-31381-8.
  3. ^ Das M, Bandyopadhyay D, Singh RP, Harde H, Kumar S, Jain S (January 2012). "Orthogonal biofunctionalization of magnetic nanoparticles via "clickable" poly(ethylene glycol) silanes: a "universal ligand" strategy to design stealth and target-specific nanocarriers". Journal of Materials Chemistry. 22 (47): 24652. doi:10.1039/C2JM34571D.
  4. ^ Tehrani, Z.; Thomas, D. J.; Guy, O. J. (2016). "Electrochemical Biofunctionalization of Highly Oriented Pyrolytic Graphite for Immunosensor Applications" (PDF). e-Journal of Surface Science and Nanotechnology. 14: 193–197. doi:10.1380/ejssnt.2016.193. ISSN 1348-0391.
  5. ^ de Mel A, Jell G, Stevens MM, Seifalian AM (November 2008). "Biofunctionalization of biomaterials for accelerated in situ endothelialization: a review". Biomacromolecules. 9 (11): 2969–79. doi:10.1021/bm800681k. PMID 18831592.
  6. ^ Hanawa T (December 2011). "A comprehensive review of techniques for biofunctionalization of titanium". J Periodontal Implant Sci. 41 (6): 263–72. doi:10.5051/jpis.2011.41.6.263. PMC 3259234. PMID 22324003.


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