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This fourth chapter takes a closer look at vendors who market instruments, software, and other equipment to cannabis testing laboratories.
4. Cannabis testing instruments, software, and equipment
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908 Devices, Inc.
Main landing page for cannabis testing: https://908devices.com/products/g908/
908 Devices, Inc. develops and distributes chemical analysis tools based on mass spectrometry. The company markets its G908 to the cannabis industry.
Instruments and methods
- G908, a high-pressure mass spectrometry instrument for separation and quantitative analysis
AB Sciex Pte. Ltd.
Main landing page for cannabis testing: https://sciex.com/applications/food-and-beverage-testing/cannabis-testing
Commonly known as Sciex, AB Sciex Pte. Ltd. develops "solutions in mass spectrometry paired with capillary electrophoresis and liquid chromatography."[1] The company markets some of its solutions for cannabis lab testing, including[2]:
- potency testing
- mycotoxin testing
- pesticide testing
- terpene testing
Instruments and methods
Triple Quad systems
Sciex offers four different Triple Quad systems for tandem mass spectrometry paired with liquid chromatography (LC-MS/MS): the 6500+, 5500, 4500, and 3500. The company claims that with these systems "scientists can acquire multiple reaction monitoring (MRM), precursor, neutral loss, and product ion scans to develop powerful methods for complex matrices, all while maintaining reproducibility and robustness."[3]
QTRAP systems
Sciex also offers three different Triple Quad Linear Ion Traps (QTRAP) systems for LC-MS/MS: the 6500+, 5500, and 4500. The company states that these are similar to the Triple Quad systems "but with enhanced scan functions to enable simultaneous quantitation and confirmation."[4]
vMethod for Cannabis
Sciex also offers a "vMethod," a quantitation method for pesticide and cannabinoid analysis, that works on many of their LC-MS/MS systems.[5]
Agilent Technologies, Inc.
Main landing page for cannabis testing: https://www.agilent.com/en/promotions/cannabis
Agilent Technologies, Inc. is an instrument and software development company for the life sciences, diagnostics, and applied chemical industries. The company offers a variety of chromatography and spectrometry instruments (using a wide array of techniques) and software for the cannabis testing industry, including[6]:
- potency and efficacy testing
- heavy metals testing
- pesticide testing
- residual solvents testing
- terpene testing
Instruments and methods
The company suggests instrument options based on what type of testing will occur.[6]
Potency and efficacy testing
- 1260 Infinity II SFC System: a supercritical fluid chromatography (SFC) system with an ultra-high performance liquid chromatography (UHPLC) power range
- 1290 Infinity II LC System: an UHPLC system
- 1290 Infinity II 2D-LC System: similar to the prior, but with two-dimensional liquid chromatography
- 5977B GC/MSD: a single-quadrupole GC/MS system with an electron ionization (EI) source
- Cary 630 FTIR Spectrometer: portable fourier-transform infrared (FTIR) spectroscopy
- Intuvo 9000 GC System: an ultra-fast gas chromatography system
Heavy metals testing
- 5110 ICP-OES Instrument: an inductively coupled plasma optical emission spectrometry (ICP-OES) instrument with synchronous radial and axial measurement
- 7800 ICP-MS: an inductively coupled plasma mass spectrometry (ICP-MS) instrument
- 7900 ICP-MS: an inductively coupled plasma mass spectrometry (ICP-MS) instrument with higher matrix tolerance, wider dynamic range, and better signal-to-noise ratio
- 8900 Triple Quadrupole ICP-MS: an inductively coupled plasma normal and tandem mass spectroscopy instrument with triple quadrupole
Pesticide testing
- 6400 Triple Quadrupole LC/MS: liquid chromatography normal and tandem mass spectrometry instruments, with four variations (6420A, -60C, -70A, and 95B)
- 6500 Series Accurate-Mass Quadrupole Time-of-Flight (Q-TOF) LC/MS: quadrupole time-of-flight liquid chromatography-mass spectrometry instruments, with five variations (6530, -45, -45XT, -50, and -60)
- 7000D Triple Quadrupole GC/MS: a gas chromatography normal and tandem mass spectroscopy instrument with triple quadrupole and dynamic MRM
- GC/MS/MS Pesticides Analyzer: a gas chromatography tandem mass spectroscopy instrument with triple quadrupole
Residual solvents testing
- 7890 Series GC with 7697A Headspace Sampler and Flame Ionization Detector: a gas chromatography instrument combined with the 7697A Headspace Sampler and compatible flame ionization detector
Terpene testing
- 1260 Infinity II Diode Array Detector HS: a liquid chromatography high-sensitivity diode array detector
- 1260 Infinity II Diode Array Detector WR: a liquid chromatography wide-range diode array detector
- 7890 Series GC: a gas chromatography instrument
- Intuvo 9000 GC System: an ultra-fast gas chromatography system
Software
- ICP Expert Software for ICP-OES: inductively coupled plasma optical emission spectrometry (ICP-OES) software for data analysis
- MassHunter: mass spectrometry software for instrument control, monitoring, and data analysis
- MicroLab: fourier-transform infrared spectroscopy software for quantitative method development, calibrations, and data analysis
Alpha-CAT Lab s.r.o.
Main landing page for cannabis production: https://www.alpha-cat.org/the-test/how-it-works/
alpha-CAT Lab s.r.o. is a cannabis testing and equipment manufacturing business based in Prague, Czech Republic. The company not only runs cannabis testing laboratories in Europe but also develops the alpha-CAT cannabinoid analysis tool "which combines the simple analytical technique of thin-layer chromatography (TLC) with specific thin-layers and developing fluid."[7] Consult the website for more information.
BÜCHI Labortechnik AG
Main landing page for cannabis production: https://www.buchi.com/en/cannabis-application-booklet
BÜCHI Labortechnik AG is laboratory technology development company for research and development, quality control, and production operations globally. The company offers a variety of instruments and equipment for cannabis production workflow, including[8]:
- post-chromatography and post-extraction solvent concentration
- preperative chromatography for purification of cannabinoids
- microencapsulation of CBD into gelatin beads/soft oil core capsules
- formulation of CBD into an inhalable/edible dry powder
See the Theory & Applications booklet (main landing page) for more details on how to integrate the equipment for each activity.
Instruments and methods
The company suggests instrument options based on what type of production activity will occur.[8]
Post-chromatography and post-extraction solvent concentration
- Rotavapor R-220 Pro: an industrial evaporator with programmable methods, automatic distillation, and remote monitoring options
- F-325 Recirculating Chiller
- V-600 Vacuum Pump
Preparative chromatography for purification of cannabinoids
- Reveleris X2: flash column chromatography for separations and flash purification; more advanced than the Sepacore
- Sepacore Flash Systems X10/X50: flash column chromatography for separations and flash purification
- C-601 Pump
- C-650 ELS Detector: an evaporative light scattering detector for any mobile phase or gradient
Microencapsulation of CBD into gelatin beads/soft oil core capsules
- Encapsulator B-390
- Encapsulator B-395 Pro
- Rotavapor R-300: a rotary evaporator
- Interface I-300 Pro
- F-305 Recirculating Chiller
- V-300 Vacuum Pump
Formulation of CBD into an inhalable/edible dry powder
CEM Corporation
Main landing page for cannabis testing: http://cem.com/cannabis
CEM Corporation is laboratory instrumentation and method design and development company, with a focus on compositional analysis of food and other samples, as well acid digestion and chemical synthesis. CEM specifically offers two different instruments for cannabis testing and analysis labs, including instruments for the[9]:
- extraction for potency, pesticide, terpene, and mycotoxin testing
- microwave digestion of oils, edibles, and plant material (before, e.g., inductively coupled plasma mass spectroscopy)
Instruments and methods
- EDGE: an automated instrument for energized dispersive extraction and dispersive solid-phase extraction (dSPE)
- MARS 6: a microwave digestion system with hundreds of preprogrammed methods
Emerald Scientific, LLC
Main landing page for cannabis testing: https://emeraldscientific.com/
Emerald Scientific, LLC calls their business "[t]he first and only company 100% dedicated to distributing scientific supplies and equipment to the cannabis industry."[10] The company lists a wide variety of instruments, equipment, and consumables for cannabis testing, production, and extraction laboratories. Emerald acts as a distributor of other products, and thus the inventory may change. Examples of inventory include:
- sample preparation supplies
- solvents
- mass spectrometry columns
- heating mantles
- chillers and circulators
- vacuum pumps and tubing
- reference standards
- culture media
- safety equipment
Consult the Emerald website to see all they offer.
Fritsch GmbH
Main landing page for cannabis testing: https://www.fritsch-international.com/sample-preparation/applications-solutions/ (select "Cannabis" from Industry option)
Fritsch GmbH manufactures sample preparation and particle sizing equipment for laboratories. The company lists one instrument specifically for the cannabis industry.
Instruments and methods
- Universal Cutting Mill PULVERISETTE 19: a cutting mill "to finely mill cannabis plant material in preparation for SFE processes," noting that "[t]he efficient and precise reduction in particle size optimizes oil output and formulation."[11]
GemmaCert Ltd.
Main landing page for cannabis testing: https://gemmacert.com/
GemmaCert Ltd. is a cannabis testing technology company that markets the GemmaCert analysis tool.
Instruments and methods
- GemmaCert: a portable near-infrared spectroscopy instrument designed to analyze total THC and total CBD levels, without destroying the inserted specimen[12]; see the specifications sheet for more information
GenTech Scientific, Inc.
Main landing page for cannabis testing: https://gentechscientific.com/214-cannabis-testing-instruments
GenTech Scientific, Inc. is a distributor of refurbished laboratory analytical instruments. The company states they "guarantee OEM standards at a fraction of the cost of new instruments, and we provide one year warranty on all GenTech certified used lab instruments."[13] Top instruments include chromatography and spectrometry equipment, and GenTech also offers new consumable kits. Inventory changes regularly, so visit their website often for the latest.
LGC Limited
Main landing page for cannabis testing: https://us.lgcstandards.com/US/en/search?text=cannabis
LGC Limited—operating as LGC Standards—manufactures and distributes reference materials and proficiency testing schemes for a variety of industries. Among its offerings are cannabis-related testing reference standards for pesticides, residual solvents, and terpenes. Consult the vendor's web store or contact them directly to learn about their entire stock of reference materials.
Marshall Scientific, LLC
Main landing page for cannabis testing: https://www.marshallscientific.com/Cannabis_Testing_Laboratory_Equipment_a/1582.htm
Marshall Scientific, LLC is a distributor of refurbished laboratory equipment for a variety of clinical and research laboratories. The company markets some of its refurbished equipment for cannabis extraction and testing activities, including:
- high-performance liquid chromatography systems
- rotary evaporators
- benchtop centrifuges
- vacuum ovens
- analytical balances
- micropipette sets
Stock changes regularly, so visit their website often for the latest.
Microbiologics, Inc.
Main landing page for cannabis testing: http://www.microbiologics.com/cannabis
Microbiologics, Inc. develops and distributes biometerials. Among them, the company markets equipment and consumables for microbial testing of cannabis. Materials for growing reference cultures, bundled sets and panels of microorganisms, self-contained strains, and molecular standards are among Microbiologics' offerings. Consult their website for more details.
Neutec Group, Inc.
Main landing page for cannabis testing: https://www.neutecgroup.com/cannabis
Neutec Group, Inc. provides equipment and support services to quality control and research and development laboratories. Neutec offers equipment solutions for cannabis testing labs testing for microbiological contaminates and water activity. This includes colony counters, water activity meters, multispectral imaging solutions, and air samplers. Consult their website for more details.
Orange Photonics, Inc.
Main landing page for cannabis testing: http://www.orangephotonics.com/
Orange Photonics, Inc. ia a cannabis testing technology company that markets the LightLab cannabis analyzer.
Instruments and methods
- LightLab: a portable high-performance liquid chromatography selective separation spectroscopy instrument for cannabis potency analysis; the optional Terpenes+ module also allows for terpenes analysis.[14]
Peak Scientific Instruments Ltd.
Main landing page for cannabis testing: https://www.peakscientific.com/blog/what-are-the-most-common-forms-of-cannabis-analysis/
Peak Scientific Instruments Ltd. designs, manufactures, and distributes high-performance gas generators for laboratories. In a November 2018 blog post, the company outlined how its many gas generation solutions could be paired with specific third-party analytical instruments for the various types of cannabis testing.[15] Peak offers solutions for:
- potency and efficacy testing
- heavy metals testing
- mycotoxins analysis
- pesticide testing
- residual solvents testing
- terpene testing
Instruments and methods
The company suggests gas generation options based on what type of testing will occur.[15]
Potency and efficacy testing
- Precision series: modular gas generators for gas chromatography, including nitrogen, hydrogen, zero air, and compressed air gas generators; recommends pairing with Agilent Intuvo 9000 GC and Agilent 5977B GC/MSD instruments
- Solaris XE 35: a nitrogen generator for liquid chromatography mass spectrometry or low-flow nitrogen instruments; recommends pairing with the various Agilent 1290 Infinity II series instruments
Heavy metals testing
- Precision Hydrogen Trace 250: a hydrogen generator designed primarily for gas chromatography carrier gas use, as well as flame ionization and flame photometric detection, and inductively coupled plasma mass spectrometry; recommends pairing with the Agilent 7800/7900 ICP-MS and Agilent 8900 Triple Quadrupole ICP-MS
- NG5000 and NG5000A: ultra-high purity nitrogen generators, with the NG5000A having its own internal compressor; recommends pairing with the Agilent 5110 ICP-OES
Mycotoxins analysis
- Infinity 1051, Genius 1051, and Genius 3051: nitrogen and dry air generators for liquid chromatography mass spectrometry, with the 3051 being recommend over the 1051 if high-flow gas delivery mode is required; recommends pairing with the Shimadzu LCMS-8050 Triple Quadrupole Mass Spectrometer
- Genius 1024 and Infinity 1031: nitrogen and dry air generators for liquid chromatography mass spectrometry; recommends pairing with the SCIEX Triple Quad or QTRAP 6500+ system
Pesticide testing
- Infinity 1051, Genius 1051, and Genius 3051: nitrogen and dry air generators for liquid chromatography mass spectrometry, with the 3051 being recommend over the 1051 if high-flow gas delivery mode is required; recommends pairing with the Shimadzu LCMS-8050 Triple Quadrupole Mass Spectrometer
- Genius 1024, Genius AB-3G, and Infinity 1031: nitrogen and dry air generators for liquid chromatography mass spectrometry; recommends pairing with the SCIEX ExionLC AC HPLC System, in conjunction with the SCIEX QET 4500 LC-MS/MS System
- Precision series: modular gas generators for gas chromatography, including nitrogen, hydrogen, zero air, and compressed air gas generators; recommends pairing with Agilent Intuvo 9000 GC and Agilent 5977B GC/MSD instruments; recommends pairing with the Agilent 7000 Series Triple Quadrupole GC/MS and the Agilent GC/MS/MS Pesticides Analyzer
- Solaris XE 35 and Genius XE 35: a nitrogen generator for liquid chromatography mass spectrometry or low-flow nitrogen instruments, as well as evaporative light scattering detection in the case of the Genius; recommends pairing with the Agilent 6400 Series Triple Quadrupole LC/MS
- Solaris XE 35, Infinity XE 5010, Genius XE 35, and Genius XE 70: nitrogen generators for various purposes, depending on the model, though largely liquid chromatography mass spectrometry and evaporative light scattering detection; recommends pairing with the Agilent 6500 Series Accurate-Mass Quadrupole Q-TOF LC/MS
Residual solvents testing
- Precision Nitrogen Headspace 250: a nitrogen generator for gas chromatography with headspace sampler requirements; recommends pairing with the Shimadzu Nexis GC-2030 with HS-20 Headspace Sampler or the GCMS-TQ8050 with Headspace Sampler
- Precision series: modular gas generators for gas chromatography, including nitrogen, hydrogen, zero air, and compressed air gas generators; recommends pairing with Agilent 7890 Series GC and the Agilent Flame Ionization Detector
Terpene testing
- Precision series: modular gas generators for gas chromatography, including nitrogen, hydrogen, zero air, and compressed air gas generators; recommends pairing with the Shimadzu GCMS-TQ8050 Triple Quadrupole Gas Chromatograph Mass Spectrometer, the Agilent Intuvo 9000 GC, and the Agilent 7890 Series GC
- Genius 1024 and Infinity 1031: nitrogen and dry air generators for liquid chromatography mass spectrometry; recommends pairing with the SCIEX Triple Quad or QTRAP 6500+ system
- Solaris XE 35: a nitrogen generator for liquid chromatography mass spectrometry or low-flow nitrogen instruments; recommends pairing with the Agilent 1260 Infinity II Diode Array Detector
PerkinElmer, Inc.
Main landing page for cannabis testing: http://www.perkinelmer.com/category/cannabis-analysis
PerkinElmer, Inc. is a scientific technology company developing and distributing solutions "for better detection, imaging, and informatics" in the laboratory.[16] The company discusses the research area of cannabis analysis on its website, recommending instrument and consumables solutions for cannabis testing laboratories, including[17]:
- potency and efficacy testing
- heavy metals testing
- mycotoxins analysis
- pesticide testing
- residual solvents testing
- terpene testing
Instruments and methods
The company suggests instrument options based on what type of testing will occur.[17]
Potency and efficacy testing
- Flexar HPLC: a high-performance liquid chromatography system, that can be used with a quaternary pump, autosampler with Peltier cooling, column heater, and photodiode array detector to detect cannabinoids
- Spectrum Two FTIR: a fourier transform near-infrared spectrometry device that uses nondestructive methods
Heavy metals testing
- NexION ICP-MS, with a Titan MPS: an inductively coupled plasma mass spectroscopy device that can be used in conjunction with the Titan MPS microwave digestion processing tool
Mycotoxins analysis
- QSight 220: an ultra-high-performance liquid chromatography tandem mass spectrometry instrument
Pesticide testing
- QSight 220: an ultra-high-performance liquid chromatography tandem mass spectrometry instrument
Residual solvents testing
- Clarus SQ 8 GC/MS, with a TurboMax headspace sampler: a headspace gas chromatography mass spectrometry instrument
Terpene testing
- Clarus SQ 8 GC/MS, with a TurboMax headspace sampler: a headspace gas chromatography mass spectrometry instrument
Software
- iLab: a laboratory execution system that automates testing, data collection, and reporting
- ChemDraw: software for drawing chemical structures and biological pathways
- Simplicity 3Q: software for workflow management
Quantum Analytics, LLC
Main landing page for cannabis testing: https://www.lqa.com/markets/cannabis/
Quantum Analytics is a distributor of laboratory analytical instruments. The company markets several of its third-party instruments to cannabis laboratories for applications such as[18]:
- potency and efficacy testing
- heavy metals testing
- mycotoxins analysis
- pesticide testing
- residual solvents testing
- terpene testing
Consult their website or cannabis capabilities flyer for more information.
Restek Corporation
Main landing page for cannabis testing: https://www.restek.com/Landing-Pages/Cannabis
Restek Corporation develops and manufactures chromatography columns and accessories for a wide variety of industries. The company offers a wide variety of supplies for the cannabis testing industry, including[19]:
- chromatography columns
- certified reference standards
- sample preparation and management supplies
- consumables and accessories for chromatography instruments
Consult their website or catalog to review all their cannabis testing supplies.
Sage Analytics
Main landing page for cannabis testing: http://sageanalytics.com/
Sage Analytics develops and manufactures potency testing solutions for the cannabis testing industry.
Instruments and methods
- Profiler II Humboldt Special Edition: a portable near-infrared spectroscopy device for testing cannabis potency
- Profiler II Humboldy Mini: same as the Special Edition but smaller and more lightweight
- Beacon: a portable near-infrared spectroscopy device for testing cannabis potency, with an onboard touchscreen; also comes without a touchscreen, marketed as the Luminary Profiler
Scientific Repair, Inc.
Main landing page for cannabis testing: https://www.srigc.com/cn/downloads/1/Model420GCSept2016%20(2).pdf
Commonly known as SRI Instruments, Scientific Repair, Inc. manufactures and distributes chromatography instruments and accessories. Their 26-page guide on gas chromatographs for cannabis testing lists three primary instruments and describes their practical use for[20]:
- potency and efficacy testing
- residual solvents testing
- terpene testing
Instruments and methods
The company suggests instrument options based on what type of testing will occur.[20]
Potency and efficacy testing
- Model 310C-MM: a gas chromatography with flame ionization detection instrument, with additional columns for extended analyses
- Model 420 GC: a gas chromatography with flame ionization detection instrument
- Model 8610C: a gas chromatography with flame ionization detection instrument, with optional columns for additional analyses
Residual solvents testing
- Model 310C-MM: a gas chromatography with flame ionization detection instrument, with additional columns for extended analyses
- Model 8610C: a gas chromatography with flame ionization detection instrument, with optional columns for additional analyses
Terpene testing
- Model 310C-MM: a gas chromatography with flame ionization detection instrument, with additional columns for extended analyses
- Model 8610C: a gas chromatography with flame ionization detection instrument, with optional columns for additional analyses
Software
- PeakSimple: chromatography software for SRI's chromatography instruments
Shimadzu Scientific Instruments, Inc.
Main landing page for cannabis testing: https://www.ssi.shimadzu.com/industry/cannabis-testing-solutions.html
Shimadzu Scientific Instruments, Inc. is a multi-divisional corporation that focuses on creating and distributing medical diagnostic, aerospace, and analytical instrument solutions for a variety of industries. Among their solutions are chromatography, spectrometry, and other cannabis testing solutions for laboratories for purposes of[21]:
- potency and efficacy testing
- heavy metals testing
- moisture content analysis
- mycotoxins analysis
- pesticide testing
- residual solvents testing
- terpene testing
Instruments and methods
The company suggests instrument options based on what type of testing will occur, via their cannabis testing brochure. Additionally, they offer two advanced tools for research:
- Nexera UC: a supercritical fluid extraction and supercriticial fluid chromatography liquid chromatography tandem mass spectrometry instrument
- MALDI iD-Plus: a microbial identification system
Potency and efficacy testing
- Cannabis Analyzer for Potency: a high-performance liquid chromatography instrument with three methods: high-throughput, high-sensitivity, and high-resolution
Heavy metals testing
- ICPMS-2030: an inductively coupled plasma mass spectroscopy instrument
Moisture content analysis
- MOC63u Moisture Balance: a moisture balance with five preset measurement programs
- MOC-120H Moisture Balance: a moisture balance with nine preset measurement programs
Mycotoxins analysis
- LCMS-8050: a liquid chromatography tandem mass spectrometry instrument
Pesticide testing
- GCMS-TQ8050: a triple quadrupole gas chromatography tandem mass spectrometry instrument that can be paired with the AOC-6000 or AOC-20i headspace autosamplers
- LCMS-8050: a liquid chromatography tandem mass spectrometry instrument
Residual solvents testing
- GCMS-TQ8050: a triple quadrupole gas chromatography tandem mass spectrometry instrument that can be paired with the AOC-6000 or AOC-20i headspace autosamplers
- Nexis GC-2030: a gas chromatography instrument paired with the HS-20 headspace sampler
Terpene testing
- GCMS-TQ8050: a triple quadrupole gas chromatography tandem mass spectrometry instrument that can be paired with the HS-20 headspace sampler and NIST Mass Spectral Library
Software
- LabSolutions: a suite of software tools that allows users to control instruments and view instrument data, and it can create and export files (spreadsheets) of instrument data that can be mapped to a database in an interfaced laboratory information management system (LIMS)
Sigma-Aldritch, Inc. / MilliporeSigma, Inc.
Main landing page for cannabis testing: https://www.sigmaaldrich.com/analytical-chromatography/food-safety/cannabis-testing.html
Note: Sigma-Aldritch, Inc. was acquired by Millipore and became MilliporeSigma, Inc. The Sigma-Aldritch website is still active and demonstrates its cannabis testing materials; however, the website will likely change in the future.
Sigma-Aldritch, Inc., which has become MilliporeSigma, Inc., distributes lab materials and technologies for various industries. This includes the cannabis testing industry, with supplies like[22]:
- chromatography columns
- certified reference materials
- solvents and reagents
- sample preparations kits
- laboratory equipment
See their cannabis testing catalog for more details.
SPEX CertiPrep, Inc.
Main landing page for cannabis testing: https://www.spexcertiprep.com/products/cannabis
SPEX CertiPrep, Inc. is a distributor of certified reference materials and sample preparation equipment for analytical spectroscopy. The company markets standards for many types of cannabis testing, as well a few sample preparation instruments such as mills and grinders. Consult their website for available supplies, as well as their online standards catalog.
Thermo Fisher Scientific
Main landing page for cannabis testing: https://www.thermofisher.com/us/en/home/products-and-services/promotions/industrial/cannabis-testing-canada.html
Thermo Fisher Scientific is a multi-divisional corporation that develops, manufactures, and distributes a wide variety of technologies for research and analytical laboratories. The company has begun marketing cannabis testing solutions to the Canadian market with its 2018 legalization campaign complete. Among its offerings are solutions for[23]:
- potency and efficacy testing
- heavy metals testing
- mold and bacteria analysis
- mycotoxins analysis
- pesticide testing
- residual solvents testing
Aside from instruments, Thermo Fisher also lists a variety of chromatography columns and sample preparation kits for each type of testing. Consult the website for more on these items.
Instruments and methods
The company suggests instrument options based on what type of testing will occur.[23]
Potency and efficacy testing
- Vanquish UHPLC Systems: three different ultra-high-performance liquid chromatography instruments: Vanquish Horizon, Flex, and Duo
- UltiMate 3000 HPLC Systems: high- and ultra-high-performance liquid chromatography systems, with four different variations of preparation
- TSQ Altis and TSQ Quantis: liquid chromatography tandem mass spectrometry with triple-stage quadrupole instruments, with the Quantis having greater mass range
- Q Exactive Hybrid: liquid chromatography mass spectrometry that has "quadruple precursor ion selection with high-resolution, accurate-mass (HRAM) Orbitrap detection"
- TRACE 1310: a gas chromatography / gas chromatography mass spectrometry instrument
- ISQ 7000: gas chromatography mass spectrometry with single quadrupole
- Exactive GC Orbitrap: gas chromatography mass spectrometry with Orbitrap technology
- Q Exactive GC Orbitrap: gas chromatography tandem mass spectrometry with Orbitrap technology
Heavy metals testing
- iCAP 7000 Series ICP-OES: a series of inductively coupled plasma optical emission spectrometry instruments: the 7200, 7400, and 7600
- iCAP RQ ICP-MS: an inductively coupled plasma mass spectrometry instrument with single quadrupole
- iCAP TQ ICP-MS: an inductively coupled plasma mass spectrometry instrument with triple quadrupole
Mold and bacteria analysis
- QuantStudio 5 Food Safety Real-Time PCR System: a polymerase chain reaction instrument
- [https://www.thermofisher.com/us/en/home/life-science/pcr/real-time-pcr/real-time-pcr-instruments.html other QuantStudio series PRC devices: other polymerase chain reaction instruments that vary based on need
Mycotoxins analysis
- Vanquish UHPLC Systems: three different ultra-high-performance liquid chromatography instruments: Vanquish Horizon, Flex, and Duo
- UltiMate 3000 HPLC Systems: high- and ultra-high-performance liquid chromatography systems, with four different variations of preparation
- TSQ Altis and TSQ Quantis: liquid chromatography tandem mass spectrometry with triple-stage quadrupole instruments, with the Quantis having greater mass range
- Q Exactive Hybrid: liquid chromatography mass spectrometry that has "quadruple precursor ion selection with high-resolution, accurate-mass (HRAM) Orbitrap detection"
Pesticide testing
- Vanquish UHPLC Systems: three different ultra-high-performance liquid chromatography instruments: Vanquish Horizon, Flex, and Duo
- UltiMate 3000 HPLC Systems: high- and ultra-high-performance liquid chromatography systems, with four different variations of preparation
- TSQ Altis and TSQ Quantis: liquid chromatography tandem mass spectrometry with triple-stage quadrupole instruments, with the Quantis having greater mass range
- Q Exactive Hybrid: liquid chromatography mass spectrometry that has "quadruple precursor ion selection with high-resolution, accurate-mass (HRAM) Orbitrap detection"
- ISQ 7000: gas chromatography mass spectrometry with single quadrupole
- TSQ 9000: gas chromatography tandem mass spectrometry with triple quadrupole
- Exactive GC Orbitrap: gas chromatography mass spectrometry with Orbitrap technology
- Q Exactive GC Orbitrap: gas chromatography tandem mass spectrometry with Orbitrap technology
Residual solvents testing
- TRACE 1310: a gas chromatography / gas chromatography mass spectrometry instrument
- TriPlus 300: a headspace autosampler for gas chromatography and gas chromatography mass spectrometry instruments
- TriPlus RSH: an autosampler for headspace and/or liquid injection with gas chromatography and gas chromatography mass spectrometry instruments
- Instant Connect FID: a flame ionization detector compatible with the TRACE 1300 series
Software
- Chromeleon: a chromatography data system
- TraceFinder: workflow management, quantitation, and data analysis software
- Compound Discovere: software for small molecule data analysis
- Qtegra Intelligent Scientific Data Solution: control and data processing software for a range of elemental and isotopic analysis tech
- Thermo Fisher Cloud: cloud hosting service by Thermo Fisher
VICAM
Main landing page for cannabis testing: http://vicam.com/markets/mycotoxin-test/botanicals
VICAM, a subsidiary of Waters Corporation, develops and distribute mycotoxin testing supplies. While the company makes no mention of cannabis testing on its website, it does offer mycotoxin testing solutions for botanical products, primarily testing for[24]:
- Aflatoxin B1, B2, G1, G2, M1, and M2
- Ochratoxin A
Waters Corporation
Main landing page for cannabis testing: No specific cannabis page
Waters Corporation specialty measurement instruments for laboratories from a wide array of industries. Though the company doesn't have a specific cannabis landing page on its website, a search reveals numerous white papers about using its instruments in the cannabis testing realm. From those white papers Waters details that its instruments can handle cannabis testing activities such as[25][26][27][28][29]:
- potency and efficacy testing
- pesticide testing
Instruments and methods
Waters instrument options are based on what equipment was used for specific testing as indicated in its white papers. Additionally, Waters offers an extraction system for botanical matrices:
Potency and efficacy testing
- ACQUITY QDa Mass Detector: a mass detector that can bused in conjunction with UPLC, UPC2, and Alliance HPLC systems (see below) for mass confirmation of cannabinoids
- ACQUITY UPLC Systems: an ultra-high-performance liquid chromatography suite of systems, including the H-, I, and M-Class systems
- ACQUITY UPC2 System: an ultra-high-performance convergence chromatography system that uses CO2 as a primary mobile phase component
- Alliance HPLC System: a high-performance liquid chromatography instrument, with integrated solvent and sample management
Pesticide testing
- Xevo TQ-S micro with an ACQUITY UPLC system : an ultra-high-performance liquid chromatography tandem mass spectrometry instrument with triple quadrupole
Willow Industries, LLC
Main landing page for cannabis testing: https://willowindustries.com/
Willow Industries, LLC is a Colorado-based cannabis decontamination technology business and consultancy. The company produces the WillowPure, a device that allows users to reduce the microbial contamination levels of cannabis. The device comes in versions that support up to five, 20, and 40 pounds.[30] Consult the website for more details.
References
- ↑ "About Us". AB Sciex Pte. Ltd. https://sciex.com/about-us. Retrieved 20 November 2018.
- ↑ "Grow Your Cannabis Lab's Potential and Bottom Line with LC-MS/MS Analysis". AB Sciex Pte. Ltd. https://sciex.com/applications/food-and-beverage-testing/cannabis-testing. Retrieved 20 November 2018.
- ↑ "Triple Quad LC-MS/MS Systems". AB Sciex Pte. Ltd. https://sciex.com/products/mass-spectrometers/triple-quad-systems. Retrieved 21 November 2018.
- ↑ "QTRAP LC-MS/MS Systems". AB Sciex Pte. Ltd. https://sciex.com/products/mass-spectrometers/qtrap-systems. Retrieved 21 November 2018.
- ↑ "vMethod Application for Quantitation of Pesticide Residues and Cannabinoids in Cannabis Matrices 1.0". AB Sciex Pte. Ltd. https://sciex.com/products/methods/vmethod-application-for-quantitation-of-pesticide-residues-and-cannabinoids-in-cannabis-matrices-10. Retrieved 21 November 2018.
- ↑ 6.0 6.1 "Cannabis Testing Solutions". Agilent Technologies, Inc. https://www.agilent.com/en/promotions/cannabis. Retrieved 21 November 2018.
- ↑ "How it works". Alpha-CAT Lab s.r.o. https://www.alpha-cat.org/the-test/how-it-works/. Retrieved 29 November 2018.
- ↑ 8.0 8.1 "Cannabis Booklet: Theory & Applications" (PDF). BÜCHI Labortechnik AG. https://static1.buchi.com/sites/default/files/content-page/downloads/Application_Booklet_Cannabis_.pdf. Retrieved 21 November 2018.
- ↑ "Cannabis Analysis". CEM Corporation. http://cem.com/cannabis. Retrieved 21 November 2018.
- ↑ "Emerald Scientific". Emerald Scientific, LLC. https://emeraldscientific.com/. Retrieved 21 November 2018.
- ↑ "CANNABIS PLANT MATERIAL PREPARATION FOR EFFICIENT EXTRACTION". Fritsch GmbH. https://www.fritsch-international.com/sample-preparation/applications-solutions/details/solution/cannabis-plant-material-preparation-for-efficient-extraction/. Retrieved 21 November 2018.
- ↑ "GemmaCert - Technology". GemmaCert Ltd. https://gemmacert.com/index.php/tech/. Retrieved 21 November 2018.
- ↑ "GenTech". GenTech Scientific, Inc. https://gentechscientific.com/. Retrieved 21 November 2018.
- ↑ "LightLab Cannabis Analyzer". Orange Photonics, Inc.
- ↑ 15.0 15.1 McBride, B. (9 November 2018). "What are the most common forms of cannabis testing?". Peak Scientific Instruments Ltd. https://www.peakscientific.com/blog/what-are-the-most-common-forms-of-cannabis-analysis/. Retrieved 22 November 2018.
- ↑ "Discover PerkinElmer". PerkinElmer, Inc. http://www.perkinelmer.com/corporate/company/discover-PerkinElmer/index.html. Retrieved 22 November 2018.
- ↑ 17.0 17.1 "Cannabis Analysis". PerkinElmer, Inc. http://www.perkinelmer.com/category/cannabis-analysis. Retrieved 22 November 2018.
- ↑ "Cannabis Solutions: Growing Confidence". Quantum Analytics, LLC. https://www.lqa.com/markets/cannabis/. Retrieved 29 November 2018.
- ↑ "Growing Analytical Solutions for Cannabis Labs". Restek Corporation. https://www.restek.com/Landing-Pages/Cannabis#products. Retrieved 22 November 2018.
- ↑ 20.0 20.1 "SRI Gas Chromatographs for Cannabis Testing" (PDF). Scientific Repair, Inc. September 2016. https://www.srigc.com/cn/downloads/1/Model420GCSept2016%20(2).pdf. Retrieved 22 November 2018.
- ↑ "Cannabis Testing Solutions". Shimadzu Scientific Instruments, Inc. https://www.ssi.shimadzu.com/industry/cannabis-testing-solutions.html. Retrieved 22 November 2018.
- ↑ "Cannabis Testing: Quality You Can Trust" (PDF). Sigma-Aldritch, Inc. March 2017. https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma-Aldrich/General_Information/1/cannabis-testing.pdf. Retrieved 22 November 2018.
- ↑ 23.0 23.1 "Cannabis Testing in Canada". Thermo Fisher Scientific. https://www.thermofisher.com/us/en/home/products-and-services/promotions/industrial/cannabis-testing-canada.html. Retrieved 22 November 2018.
- ↑ "Botanicals". VICAM. http://vicam.com/markets/mycotoxin-test/botanicals. Retrieved 22 November 2018.
- ↑ "Building Laboratory Capacity to Ensure Cannabis Safety, Quality, and Efficacy" (PDF). Waters Corporation. August 2018. http://www.waters.com/webassets/cms/library/docs/720006394en.pdf. Retrieved 22 November 2018.
- ↑ Tran, K.; Twohig, M; Young, M. et al. (September 2018). "Determination of the Oregon Pesticide List in Cannabis Using a Simple Extraction Procedure with dSPE Cleanup and UPLC-MS/MS" (PDF). Waters Corporation. http://www.waters.com/webassets/cms/library/docs/720006373en.pdf. Retrieved 22 November 2018.
- ↑ Aubin, A.J.; Layton, C.; Helmueller, S. (November 2018). "Separation of 16 Cannabinoids in Cannabis Flower and Extracts Using a Reversed-Phase Isocratic HPLC Method" (PDF). Waters Corporation. http://www.waters.com/webassets/cms/library/docs/720006426en.pdf. Retrieved 22 November 2018.
- ↑ "Mass Confirmation of Cannabinoids in Cannabis sativa by Using HPTLC-QDa" (PDF). Waters Corporation. July 2017. http://www.waters.com/webassets/cms/library/docs/720006047en.pdf. Retrieved 22 November 2018.
- ↑ Gottardi, M.; Ferron, F.; Lee, R. et al. (September 2018). "Using UPLC-MS/MS for the Determination of Carboxy-THC (cTHC) in Hair for Forensic Toxicology" (PDF). Waters Corporation. http://www.waters.com/webassets/cms/library/docs/720006363en.pdf. Retrieved 22 November 2018.
- ↑ "WillPure". Willow Industries, LLC. https://willowindustries.com/willowpure-process/. Retrieved 29 November 2018.
Citation information for this chapter
Chapter: 4. Cannabis testing instruments, software, and equipment
Title: Past, Present, and Future of Cannabis Laboratory Testing and Regulation in the United States
Edition: Second edition
Author for citation: Shawn E. Douglas
License for content: Creative Commons Attribution-ShareAlike 4.0 International
Publication date: December 2018