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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Denuders.jpg|200px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Karaattuthazhathu NatJLabMed23 12-2.png|260px]]</div>
A '''[[denuder]]''' is a cylindrical or annular conduit or tube internally coated with a reagent that selectively reacts with a stable flow of gas drawn through the conduit. The gas molecules diffuse to the walls while the [[analyte]] contained in the gas is transmitted outwards via laminar flow, collected, and analyzed. Effectiveness of the system depends primarily "on a complete discrimination between the gas species and particulate matter."
'''"[[Journal:Sigma metrics as a valuable tool for effective analytical performance and quality control planning in the clinical laboratory: A retrospective study|Sigma metrics as a valuable tool for effective analytical performance and quality control planning in the clinical laboratory: A retrospective study]]"'''


Additional non-linear denuder geometries have also been tried with mixed results. Coiled configurations increased collection efficiency but lost larger particulate. A parallel multi-tube diffusion denuder has also been tried and found to increase collection efficiency. Other geometries include honeycombed, annular, and parallel plate. The development of the annular denuder in particular allowed researchers to overcome the inefficiencies of cylindrical denuders, allowing operation at larger flow rates (up to 30 times that of cylindrical denuders), shorter sampling periods, and less particle loss. ('''[[Denuder|Full article...]]''')<br />
For the release of precise and accurate reports of [[Medical test|routine tests]], its necessary to follow a proper [[quality management system]] (QMS) in the [[clinical laboratory]]. As one of the most popular QMS tools for process improvement, Six Sigma techniques and tools have been accepted widely in the [[laboratory]] testing process. Six Sigma gives an objective assessment of analytical methods and instrumentation, measuring the outcome of a process on a scale of 0 to 6. Poor outcomes are measured in terms of defects per million opportunities (DPMO). To do the performance assessment of each clinical laboratory [[analyte]] by Six Sigma analysis and to plan and chart out a better, customized [[quality control]] (QC) plan for each analyte, according to its own sigma value ... ('''[[Journal:Sigma metrics as a valuable tool for effective analytical performance and quality control planning in the clinical laboratory: A retrospective study|Full article...]]''')<br />
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Latest revision as of 16:52, 29 April 2024

Fig1 Karaattuthazhathu NatJLabMed23 12-2.png

"Sigma metrics as a valuable tool for effective analytical performance and quality control planning in the clinical laboratory: A retrospective study"

For the release of precise and accurate reports of routine tests, its necessary to follow a proper quality management system (QMS) in the clinical laboratory. As one of the most popular QMS tools for process improvement, Six Sigma techniques and tools have been accepted widely in the laboratory testing process. Six Sigma gives an objective assessment of analytical methods and instrumentation, measuring the outcome of a process on a scale of 0 to 6. Poor outcomes are measured in terms of defects per million opportunities (DPMO). To do the performance assessment of each clinical laboratory analyte by Six Sigma analysis and to plan and chart out a better, customized quality control (QC) plan for each analyte, according to its own sigma value ... (Full article...)
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