Difference between revisions of "Template:Article of the week"

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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig3 Eyal-Altman BMCBioinformatics2017 18.gif|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Karaattuthazhathu NatJLabMed23 12-2.png|260px]]</div>
'''"[[Journal:PCM-SABRE: A platform for benchmarking and comparing outcome prediction methods in precision cancer medicine|PCM-SABRE: A platform for benchmarking and comparing outcome prediction methods in precision cancer medicine]]"'''
'''"[[Journal:Sigma metrics as a valuable tool for effective analytical performance and quality control planning in the clinical laboratory: A retrospective study|Sigma metrics as a valuable tool for effective analytical performance and quality control planning in the clinical laboratory: A retrospective study]]"'''


Numerous publications attempt to predict cancer survival outcome from gene expression data using machine-learning methods. A direct comparison of these works is challenging for the following reasons: (1) inconsistent measures used to evaluate the performance of different models, and (2) incomplete specification of critical stages in the process of knowledge discovery. There is a need for a platform that would allow researchers to replicate previous works and to test the impact of changes in the knowledge discovery process on the accuracy of the induced models.
For the release of precise and accurate reports of [[Medical test|routine tests]], its necessary to follow a proper [[quality management system]] (QMS) in the [[clinical laboratory]]. As one of the most popular QMS tools for process improvement, Six Sigma techniques and tools have been accepted widely in the [[laboratory]] testing process. Six Sigma gives an objective assessment of analytical methods and instrumentation, measuring the outcome of a process on a scale of 0 to 6. Poor outcomes are measured in terms of defects per million opportunities (DPMO). To do the performance assessment of each clinical laboratory [[analyte]] by Six Sigma analysis and to plan and chart out a better, customized [[quality control]] (QC) plan for each analyte, according to its own sigma value ... ('''[[Journal:Sigma metrics as a valuable tool for effective analytical performance and quality control planning in the clinical laboratory: A retrospective study|Full article...]]''')<br />
 
''Recently featured'':
We developed the PCM-SABRE platform, which supports the entire knowledge discovery process for cancer outcome analysis. PCM-SABRE was developed using [[KNIME]]. By using PCM-SABRE to reproduce the results of previously published works on breast cancer survival, we define a baseline for evaluating future attempts to predict cancer outcome with machine learning. ('''[[PCM-SABRE: A platform for benchmarking and comparing outcome prediction methods in precision cancer medicine|Full article...]]''')<br />
{{flowlist |
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* [[Journal:Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems|Why do we need food systems informatics? Introduction to this special collection on smart and connected regional food systems]]
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* [[Journal:Data management challenges for artificial intelligence in plant and agricultural research|Data management challenges for artificial intelligence in plant and agricultural research]]
: ▪ [[Journal:Ten simple rules for cultivating open science and collaborative R&D|Ten simple rules for cultivating open science and collaborative R&D]]
* [[Journal:A blockchain-driven IoT-based food quality traceability system for dairy products using a deep learning model|A blockchain-driven IoT-based food quality traceability system for dairy products using a deep learning model]]
: ▪ [[Journal:Ten simple rules to enable multi-site collaborations through data sharing|Ten simple rules to enable multi-site collaborations through data sharing]]
}}
: ▪ [[Journal:Ten simple rules for developing usable software in computational biology|Ten simple rules for developing usable software in computational biology]]

Latest revision as of 16:52, 29 April 2024

Fig1 Karaattuthazhathu NatJLabMed23 12-2.png

"Sigma metrics as a valuable tool for effective analytical performance and quality control planning in the clinical laboratory: A retrospective study"

For the release of precise and accurate reports of routine tests, its necessary to follow a proper quality management system (QMS) in the clinical laboratory. As one of the most popular QMS tools for process improvement, Six Sigma techniques and tools have been accepted widely in the laboratory testing process. Six Sigma gives an objective assessment of analytical methods and instrumentation, measuring the outcome of a process on a scale of 0 to 6. Poor outcomes are measured in terms of defects per million opportunities (DPMO). To do the performance assessment of each clinical laboratory analyte by Six Sigma analysis and to plan and chart out a better, customized quality control (QC) plan for each analyte, according to its own sigma value ... (Full article...)
Recently featured: