File:Fig4 Berciano FrontNutr2022 9.jpg

Fig. 4 The past, present, and future of precision nutrition (PN). The origins of PN are linked to the discovery of inborn errors of metabolism and, later, more prevalent gene-diet interactions affecting nutrient metabolism and requirements. The contributions of nutritional genomics to PN are complemented by additional omic and input layers, providing increased predictive power of diet-related outcomes, including glycemic responses. In addition to traditional markers measured in the fasting state, insights from dynamic postprandial responses strengthen the importance of phenotypic flexibility, which is now considered a hallmark of health. Large-scale initiatives from NIH and elsewhere are refining systems biology approaches and AI-driven tools to integrate data layers, predict outcomes, and derive effective dietary recommendations tailored to the biology, environment, and specific needs of individuals. The future may offer increased opportunities for the adoption of PN, enabled by wearables that provide a user-friendly and seamless collection of dietary and health data, which will be leveraged by healthcare to lower costs and improve population health, aided by public health policies.

Berciano, S.; Figueiredo, J.; Brisbois, T.D.; Alford, S.; Koecher, K.; Eckhouse, S.; Ciati, R.; Kussmann, M.; Ordovas, J.M.; Stebbins, K.; Blumberg, J.B. (2022). "Precision nutrition: Maintaining scientific integrity while realizing market potential". Frontiers in Nutrition 9: 979665. doi:10.3389/fnut.2022.979665. 

2022

Berciano, S.; Figueiredo, J.; Brisbois, T.D.; Alford, S.; Koecher, K.; Eckhouse, S.; Ciati, R.; Kussmann, M.; Ordovas, J.M.; Stebbins, K.; Blumberg, J.B.

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