Journal:A web application to support the coordination of reflexive, interpretative toxicology testing

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Full article title A web application to support the coordination of reflexive, interpretative toxicology testing
Journal Journal of Pathology Informatics
Author(s) Pablo, Abed; Laha, Thomas J.; Breit, Nathan; Hoffman, Noah G.; Hoofnagle, Andrew N.; Baird, Geoffrey S.; Mathias, Patrick C.
Author affiliation(s) University of Washington School of Medicine
Primary contact Email: pcm10 at uw dot edu
Year published 2023
Volume and issue 14
Article # 100303
DOI 10.1016/j.jpi.2023.100303
ISSN 2153-3539
Distribution license Creative Commons Attribution 4.0 International
Website https://www.sciencedirect.com/science/article/pii/S2153353923001177
Download https://www.sciencedirect.com/science/article/pii/S2153353923001177/pdfft (PDF)

Abstract

Background: Reflexive laboratory testing workflows can improve the assessment of patients receiving pain medications chronically, but complex workflows requiring pathologist input and interpretation may not be well-supported by traditional laboratory information systems (LISs). In this work, we describe the development of a web application that improves the efficiency of pathologists and laboratory staff in delivering actionable toxicology results.

Method: Before designing the application, we set out to understand the entire workflow, including the laboratory workflow and pathologist review. Additionally, we gathered requirements and specifications from stakeholders. Finally, to assess the performance of the implementation of the application, we surveyed stakeholders and documented the approximate amount of time that is required in each step of the workflow.

Results: A web-based application was chosen for the ease of access for users. Relevant clinical data was routinely received and displayed in the application. The workflows in the laboratory and during the interpretation process served as the basis of the user interface (UI). With the addition of auto-filing software, the return on investment (ROI) was significant. The laboratory saved the equivalent of one full-time employee in time by automating file management and result entry.

Discussion: Implementation of a purpose-built application to support reflex and interpretation workflows in a clinical pathology practice has led to a significant improvement in laboratory efficiency. Custom- and purpose-built applications can help reduce staff burnout, reduce transcription errors, and allow staff to focus on more critical issues around quality.

Keywords: Python, laboratory workflows, custom web application, quality control, mass spectrometry

Background

References

Notes

This presentation is faithful to the original, with only a few minor changes to presentation, spelling, and grammar. In some cases important information was missing from the references, and that information was added.