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<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig2 Asiimwe JofTransMed21 19.png|240px]]</div>
<div style="float: left; margin: 0.5em 0.9em 0.4em 0em;">[[File:Fig1 Signoroni NatComm23 14.png|240px]]</div>
'''"[[Journal:From biobank and data silos into a data commons: Convergence to support translational medicine|From biobank and data silos into a data commons: Convergence to support translational medicine]]"'''
'''"[[Journal:Hierarchical AI enables global interpretation of culture plates in the era of digital microbiology|Hierarchical AI enables global interpretation of culture plates in the era of digital microbiology]]"'''


To drive [[Translational research|translational medicine]], modern day [[biobank]]s need to integrate with other sources of data (e.g., [[Health informatics|clinical]], [[genomics]]) to support novel data-intensive research. Currently, vast amounts of research and clinical data remain in silos, held and managed by individual researchers, operating under different standards and governance structures; such a framework impedes sharing and effective use of data. In this article, we describe the journey of British Columbia’s Gynecological Cancer Research Program (OVCARE) in moving a traditional tumor biobank, outcomes unit, and a collection of data silos into an integrated [[Open data#Policies and strategies|data commons]] to support data standardization and [[Data sharing|resource sharing]] under collaborative governance, as a means of providing the gynecologic cancer research community in British Columbia access to tissue samples and associated clinical and [[Molecular diagnostics|molecular]] data from thousands of patients ... ('''[[Journal:From biobank and data silos into a data commons: Convergence to support translational medicine|Full article...]]''')<br />
Full [[laboratory automation]] is revolutionizing work habits in an increasing number of clinical [[microbiology]] facilities worldwide, generating huge streams of [[Imaging|digital images]] for interpretation. Contextually, [[deep learning]] (DL) architectures are leading to paradigm shifts in the way computers can assist with difficult visual interpretation tasks in several domains. At the crossroads of these epochal trends, we present a system able to tackle a core task in clinical microbiology, namely the global interpretation of diagnostic [[Bacteria|bacterial]] [[Cell culture|culture]] plates, including presumptive [[pathogen]] identification. This is achieved by decomposing the problem into a hierarchy of complex subtasks and addressing them with a multi-network architecture we call DeepColony ... ('''[[Journal:Hierarchical AI enables global interpretation of culture plates in the era of digital microbiology|Full article...]]''')<br />
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Latest revision as of 15:02, 3 June 2024

Fig1 Signoroni NatComm23 14.png

"Hierarchical AI enables global interpretation of culture plates in the era of digital microbiology"

Full laboratory automation is revolutionizing work habits in an increasing number of clinical microbiology facilities worldwide, generating huge streams of digital images for interpretation. Contextually, deep learning (DL) architectures are leading to paradigm shifts in the way computers can assist with difficult visual interpretation tasks in several domains. At the crossroads of these epochal trends, we present a system able to tackle a core task in clinical microbiology, namely the global interpretation of diagnostic bacterial culture plates, including presumptive pathogen identification. This is achieved by decomposing the problem into a hierarchy of complex subtasks and addressing them with a multi-network architecture we call DeepColony ... (Full article...)
Recently featured: