Difference between revisions of "Journal:A model for design and implementation of a laboratory information management system specific to molecular pathology laboratory operations"

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Full article title A model for design and implementation of a laboratory information management system specific to molecular pathology laboratory operations
Journal The Journal of Molecular Diagnostics
Author(s) Tomlinson, Eban; Goodman, Jennifer; Loftus, Margaret; Bitto, Stephen; Carpenter, Erica; Oddo, Richard; Judis, LuAnn; Ali, Shabab; Robinson, Wyatt E.; Carver, Miranda; Ganea, Mariana; McDonnell, Kristen; O'Neill, Diane; Starbuck, Jennifer; Johnson, Eric; Meister, Erik; Pohl, Jonathan; Spildener, Jessica; Shurtleff, Sheila; Sovie, Sheryl; Melendez, Cathleen; Krebs, Pamela; Riley, Jacquelyn D.; Wensel, Christine; Astbury, Caroline; Azzato, Elizabeth M.; Bosler, David S.; Brock, Jay E.; Cook, James R.; Cheng, Yu-Weu; Tu, Zheng J.; Cruise, M.; Henricks, Walter H.; Farkas, Daniel H.
Author affiliation(s) Semaphore Solutions, Cleveland Clinic
Primary contact Email: farkasd2 at ccf dot org
Year published 2022
Volume and issue S1525-1578(22)
Page(s) 00012-5
DOI 10.1016/j.jmoldx.2022.01.002
ISSN 1525-1578
Distribution license Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Website https://www.degruyter.com/view/j/cdbme.2019.5.issue-1/cdbme-2019-0110/cdbme-2019-0110.xml
Download https://www.degruyter.com/downloadpdf/j/cdbme.2019.5.issue-1/cdbme-2019-0110/cdbme-2019-0110.xml (PDF)


The Molecular Pathology Section of Cleveland Clinic (Cleveland, OH) has undergone enhancement of its testing portfolio and processes. An electronic- and paper-based data management system was replaced with a commercially available laboratory information management system (LIMS) solution, a separate bioinformatics platform, customized test-interpretation applications, a dedicated accessioning service, and a results-releasing solution. The LIMS solution manages complex workflows, large-scale data packets, and process automation. However, a customized approach was required for the LIMS since a survey of commercially available off-the-shelf (COTS) software solutions revealed none met the diverse and complex needs of Cleveland Clinic's molecular pathology service. The project utilized the expertise of clinical laboratorians, pathologists, genetics counselors, bioinformaticians, and systems analysts in partnering with software-engineering consultants to design and implement a solution. Concurrently, Agile software development best practices were formulated, which may be emulated for scalable and cost-effective laboratory-authored software.

Keywords: molecular pathology, laboratory information management system, LIMS, bioinformatics, software development, Agile-Scrum




This presentation is faithful to the original, with only a few minor changes to presentation, grammar, and punctuation. In some cases important information was missing from the references, and that information was added. Everything else remains true to the original article, per the "NoDerivatives" portion of the distribution license.