Journal:Existing data sources in clinical epidemiology: Laboratory information system databases in Denmark
| Full article title | Existing data sources in clinical epidemiology: Laboratory information system databases in Denmark |
|---|---|
| Journal | Clinical Epidemiology |
| Author(s) | Johan F.H. Arendt, Anette T. Hansen, Søren A. Ladefoged, Henrik T. Sørensen, Lars Pedersen, Kasper Adelborg |
| Author affiliation(s) | Aarhus University Hospital, Aalborg University Hospital |
| Primary contact | Email: jfba at clin dot au dot dk |
| Editors | Dr. Eyal Cohen |
| Year published | 2020 |
| Volume and issue | 12 |
| Page(s) | 469–75 |
| DOI | 10.2147/CLEP.S245060 |
| ISSN | 1179-1349 |
| Distribution license | Creative Commons Attribution-NonCommercial 3.0 Unported |
| Website | https://www.dovepress.com/existing-data-sources-in-clinical-epidemiology-laboratory-information |
| Download | https://www.dovepress.com/getfile.php?fileID=58155 (PDF) |
 |
This article should be considered a work in progress and incomplete. Consider this article incomplete until this notice is removed. |
Abstract
Routine biomarker results from hospital laboratory information systems (LIS)—covering hospitals and general practitioners—in Denmark are available to researchers through access to the regional Clinical Laboratory Information System Research Database at Aarhus University and the nationwide Register of Laboratory Results for Research. This review describes these two data sources. The laboratory databases have different geographical and temporal coverage. They both include individual-level biomarker results that are electronically transferred from LISs. The biomarker results can be linked to all other Danish registries at the individual level using the unique identifier, the CPR number. The databases include variables such as the CPR number, date and time (hour and minute) of sampling, NPU code, and name of the biomarker, identification code for the laboratory and the requisitioner, the test result with the corresponding unit, and the lower and upper reference limits. Access to the two databases differs since they are hosted by two different institutions. Data cannot be transferred outside Denmark, and direct access is provided only to Danish institutions. It is concluded that access to data on routine biomarkers expands the detailed biological and clinical information available on patients in the Danish healthcare system. The full potential is enabled through linkage to other Danish healthcare registries.
Keywords: biomarkers, database, data resource, laboratory information systems
Data resource basics
Danish healthcare registries
Denmark has a large network of population-based healthcare registries.[1] Several supplementary issues of international medical journals have been devoted to describe these registries to facilitate their use in research.[2][3] The registries contain data on the Danish population of approximately 5.8 millions inhabitants and include data on healthcare contacts, hospital diagnoses, redeemed prescriptions, childbirths, causes of death, and a wide variety of other information. The Civil Registration System and the healthcare system in Denmark have been described in detail elsewhere.[1][4] In short, all Danish residents are assigned a unique 10-digit personal identification number, the CPR number, upon birth or immigration. The CPR number serves as the key identifier in the nationwide registration of personal data, including contacts with the healthcare system. The CPR number also allows Statistics Denmark to produce updated population statistics at the individual level on a variety of different topics, including but not limited to demographics, income, education, and healthcare use.
References
- ↑ 1.0 1.1 "The Danish health care system and epidemiological research: From health care contacts to database records". Clinical Epidemiology 11: 563–91. 2019. doi:10.2147/CLEP.S179083. PMC PMC6634267. PMID 31372058. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634267.
- ↑ "Danish population-based registers for public health and health-related welfare research: introduction to the supplement". Scandinavian Journal of Public Health 39 (7 Suppl.): 8–10. 2011. doi:10.1177/1403494811409654. PMID 21775344.
- ↑ "Danish clinical quality databases - an important and untapped resource for clinical research". Clinical Epidemiology 8: 425-427. 2016. doi:10.2147/CLEP.S113265. PMID 27843338.
- ↑ "The Danish Civil Registration System as a tool in epidemiology". European Journal of Epidemiology 29 (8): 541–9. 2014. doi:10.1007/s10654-014-9930-3. PMID 24965263.
Notes
This presentation is faithful to the original, with only a few minor changes to presentation, grammar, and spelling. In some cases important information was missing from the references, and that information was added.
